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带量采购政策下我院胰岛素使用情况分析

Analysis of Insulin Usage in the Hospital Under the Policy of Volume-based Procurement

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目的:通过对兰州大学第一医院胰岛素带量采购前后同期半年的用药情况进行分析,了解本院胰岛素使用情况及发展趋势,为临床胰岛素合理用药及治疗方案选择提供参考,探讨胰岛素带量采购对胰岛素的采购和使用的影响.方法:调取HIS系统胰岛素带量采购实施前(2021年7月-12月)与实施后(2022年7月-12月)胰岛素的使用数据,按照世界卫生组织官网提供的胰岛素限定日剂量及相关胰岛素的说明书,确定各种胰岛素的限定日剂量(DDD)值,分别统计和计算胰岛素的用药频度(DDDs)、日均费用(DDC)、排序比、使用金额和用量等的数据.结果:带量采购后半年使用量较带量采购前上涨了 21.20%,而销售金额下降了 47.69%,DDDs值带量采购后上升的有14个品规,增幅较大的(变化幅度≥50%)的是谷赖胰岛素3 mL:300 IU(赛诺菲)和精蛋白锌重组赖脯胰岛素混合注射液(25R)3 mL:300 IU(礼来);带量采购后,我院胰岛素的DDC值全部下降,降幅大于50%的品种有7个,其他品种的降幅也均大于30%,带量采购后序号比≥1的品种占比上升了 11个百分点.结论:药品带量采购政策有助于形成合理的药品价格形成机制,药费的下降可以提高慢性病患者用药的持续性、依从性,也大大减轻医保和患者的经济负担,带量采购后甘精胰岛素和德谷胰岛素成为本院胰岛素用量的增长点,而精蛋白人胰岛素用量将有大幅度下降,需在下一年度胰岛素预采购量申报工作中进行调整.新引进的品种因为临床对其疗效、安全性等认知不足,抱有疑虑,造成使用量较少,后期还需药师大力宣传.
Objective:To investigate the effect of volume-based procurement on the procurement and administration of insulin,and provide reference for rational use and the selection of therapeutic regime of insulin,the usage situation and development trend of insulin was analyzed in the hospital half a year before and after the volume-based procurement.Methods:The data of insulin administration was retrieved from HIS before(July to December 2021)and after(July to December 2022)the implementation of insulin volume-based procurement,which was used to analyze and count defined daily dose(DDD),DDDs,DDC,sorting ratio and the usage amount of insulin in the hospital according to the instructions for the limited daily dose of insulin and related insulin provided on the official website of World Health Organization.Results:Half a year after volume-based procurement,insulin usage amount increased by 21.20%compared with before,while the sales decreased by 47.69%.In addition,after volume-based procurement:the DDDs values of 14 products increased,in which insulin glulisine 3 mL:300 IU(Sanofi)and protamine zinc recombinant lysine insulin injection(25R)3 mL:300 IU(Lilly)were with larger increases(with a change range of ≥ 50%)of DDDs;the DDC value of all of insulin in the hospital decreased,in which 7 products decreased more than 50%and others decreased more than 30%;the products with sorting ratio ≥ 1 increased by 11 percent.Conclusion:The national policy of volume-based procurement contributes to form a reasonable drug price formation mechanism,and the decreases in drug costs improve the sustainability and compliance of patients with chronic diseases administrated with medicine,which meanwhile reduce the economic burden on medical insurance and patients greatly.Moreover,insulin glargine and insulin deglutinin become the growth points of insulin consumption in the hospital,while the consumption of isophane protamine recombinant human insulin decreases significantly,which should be adjusted in the declaration of insulin pre-procurement in the next year.Additionally,ascribed to the insufficient clinical awareness and misgiving of the efficacy and safety,the newly introduced varieties are with less usage,which requires the vigorous promotion by pharmacists in the future.

Volume-based purchaseInsulinDrug use frequencyAverage daily costDiabetes

古文亮、孙国祥、苏丽

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兰州大学第一医院药剂科,甘肃 兰州 730000

带量采购 胰岛素 用药频度 日均费用 糖尿病

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(13)