Study on the Effect and Mechanism of Tirofiban Combined with Conventional Therapy in Improving Cerebral In-farction Injury
Cerebral infarction is a serious brain injury caused by acute cerebral blood supply insufficiency.Its disability and mortality rate are high,which brings heavy disease burden to all countries in the world.The pathological damage process of cerebral infarction includes inflammatory factor damage,platelet activation,aggregation,and blood brain barrier damage,while platelet aggregation can cause thrombosis,causing serious consequences.Tirofiban,an antiplatelet drug,is a non-peptide plateletⅡ b/Ⅲ a receptor antagonist.It directly acts on the final pathway of platelet aggregation,and can effectively inhibit platelet aggregation without increasing the occurrence of ischemic events.The study discusses the pharmacological effects of tirofiban on reducing the damage of inflammatory factors,the damage of blood brain barrier and platelet aggregation from the perspective of tirofiban combined with conventional treatment to alleviate the cerebral infarction injury in patients,in order to provide theoretical support for the clinical use of tirofiban.
Cerebral infarctionTirofibanPlatelet aggregationGlycoprotein Ⅱ b/Ⅲ a receptor blocker
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