Analysis of the Correlation Between S100A12 and the Efficacy and Prognosis of Intravascular Therapy for Ischemic Stroke
Objective:lo analyze the correlation between S100A12 and EVT efficacy,prognosis in patients with ischemic stroke.Methods:Selecting 119 patients with ischemic stroke admitted to the First Affiliated Hospital of Nanyang Medical College from January 2021 to May 2023 as the research subjects.The serum S100A12,serum inflammatory factors,plaque stability,and neurological function before and after treatment were compared,and the association between S100A12 and patient treatment efficacy and prognosis was analyzed.Results:After treatment,S100A12,hs-CRP,MMP-9,HCY,IMT,stiffness,plaque index,NIHSS,and mRs score were all lower than before treatment,while MBI score was higher than before treatment(t=8.214,23.879,53.528,9.469,16.153,8.871,13.370,16.010,12.468,14.135;P＜0.05).S100A12 is positively correlated with hs-CRP,MMP-9,HCY,IMT,stiffness,plaque index,NIHSS,mRs scores and negatively correlated with MBI scores(P＜0.05).Conclusion:EVT treatment has significant effect on ischemic stroke.Monitoring S100A12 can guide clinical treatment to a certain extent,and achieve early prediction of adverse prognosis.
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