Etiology and Clinical Characteristics of 1 275 Children with Severe Pneumonia in Dongguan City
Objective:To analyze the etiology and clinical characteristics of severe pneumonia in children in Dongguan City,and to provide reference for clinical diagnosis and treatment.Methods:The pathogen detection,imaging data,clinical diagnosis and prognosis of 1 275 children with severe pneumonia admitted to the hospital from January 2018 to December 2022 were retrospectively analyzed.Results:The majority of 1 275 cases of severe pneumonia were infants＜1 year old(56.7％),with the highest incidence in summer(26.35％)and autumn(31.22％).The main clinical manifestations of fever,cough,shortness of breath,wheezing,cyanosis,and combined with cardiopulmonary diseases were more common.Bacterial infection(21.7％)and atypical pathogen infection(21.3％)were the main pathogens detected.The top 5 pathogens detected were mycoplasma pneumoniae,respiratory syncytial virus,haemophilus influenzae,streptococcus pneumoniae and adenovirus.There were 98 cases of lung consolidation and 48 cases of pleural effusion.The main cases of lung consolidation were bacterial and mixed infection,and the most common pleural effusion was mycoplasma pneumoniae infection.Drag treatment included antibiotics(83.0％),methylprednisolone sodium succinate(22.4％),immunoglobulin(8.4％),etc.211 cases(16.54％)were treated with mechanical ventilation.Virus and mixed infection were common in mechanical ventilation,and atypical pathogen infection was the least.Conclusion:Severe pneumonia in children in Dongguan is most likely to occur in infants under＜1 year old,with a high incidence in summer and autumn.It is mainly caused by bacterial and atypical pathogens,and the most common pathogens are mycoplasma pneumoniae,respiratory syncytial virus and haemophilus influenzae,etc.Respiratory syncytial virus is the most common infection in infants of＜3 months old.Respiratory syncytial virus and haemophilus influenza are the most common infections in infants aged 3 months～1 years old,and mycoplasma pneumoniae is the most common infection in children＞1 year old.Mycoplasma pneumoniae is more likely to be combined with pleural effusion,and viral and mixed infections are more likely to lead to respiratory failure.
NETL
NSTL
万方数据
