Analysis of Pathogenic Bacteria Distribution,Drug Resistance and Risk Factors in Burn Infection Patients
Objective:To investigate the distribution characteristics of pathogens in patients with burn infection,and analyze drug resistance and risk factors,in order to provide theoretical basis for pathogens in clinical burn patients.Methods:Clinical data of 279 burn patients hospitalized in Burn Department of Changyuan People's Hospital from January 2020 to December 2022 were retrospectively collected,and they were divided into infected group(79 cases)and uninfected group(200 cases)according to whether infection occurred.The etiological characteristics,drug resistance and risk factors of patients in the infected group were statistically analyzed.Results:A total of 98 strains of pathogens were detected in 79 burn infection patients,of which 63 were Gram-negative,accounting for 64.29％.The main pathogens were Pseudomonas aeruginosa,Acinetobacter baumannii and Klebsiella pneumoniae.There were 34 Gram-positive strains,accounting for 34.69％,mainly Staphylococcus aureus and Staphylococcus epidermidis.1 case was fungal,accounting for 1.02％.Among gram-negative bacteria,the resistance rate of Pseudomonas aeruginosa to ceftazidme and levofloxacin was the highest,reaching 21.74％.The resistance rate of Acinetobacter baumannii to ciprofloxacin was the highest,reaching 78.57％.The resistance rate of Klebsiella pneumoniae to ceftazidime and gentamicin was the highest(83.33％),and the resistance rate of Staphylococcus aureus to penicillin was the highest(91.30％).The resistance of Staphylococcus epidermidis to penicillin can reach 100.00％.There were significant differences in burn area,burn depth,hypovolemic shock,antibiotics and wound medication between infected group and non-infected group(χ2=28.455,23.460,24.144,29.033,22.176;P<0.05).Logistic regression analysis of wound infection in burn patients showed that burn area>30％,burn depth up to degree Ⅲ,hypovolemic shock,≥3 kinds of antibiotics and≥3 kinds of wound drugs were independent risk factors for wound infection in burn patients.Conclusion:The main pathogens in burn infection patients are gram-negative bacteria.Antibiotics can be rationally selected according to the drug resistance of pathogen.Early intervention combined with infection risk factors can reduce the risk of infection.
NETL
NSTL
万方数据
