Effects of Propofol Combined with Sevoflurane on Pregnant and Lying-in Women Undergoing Cesarean Section
Objective:To study the anesthesia effect of propofol+sevoflurane in cesarean section.Methods:80 puerperae who underwent cesarean delivery in the hospital from January 2019 to December 2021 selected as the research sample with retrospective analysis,and the patients were divided into the combined group(n=40,propofol+sevoflurane anesthesia)and routine group(n=40,routine anesthesia).The wake-up quality,basal signs,oxidative stress response,cognitive function changes and occurrence adverse events of the two groups were compared.Results:The duration of eye opening and VAS and SAS scores were lower in the combined group under propofol and sevoflurane anesthesia,and the differences were statistically significant(t=16.875,12.583,15.229;P＜0.05).After operation,HR,SPO2 and MAP of the combined group were similar to those of the conventional group after anesthesia with propofol and sevoflurane,with no statistical significance(t=1.273,1.656,0.209;P＞0.05).After operation,the oxidative stress reaction of the combined group was lighter,the corresponding AT-Ⅱ and Cor levels were lower,and the corresponding SOD levels were higher,with statistically significant difference(t=2.523,2.595,2.117;P＜0.05).After operation,the cognitive function of the combined group was relatively better,and the corresponding MMSE and MoCA scores were higher,with statistically significant difference(t=29.144,23.477;P＜0.05).The incidence of adverse drug reactions and adverse pregnancy outcomes after propofol combined with sevoflurane anesthesia in the combined group was lower,and the difference was statistically significant(χ2=8.824,P＜0.05).Conclusion:Compared with conventional anesthesia,propofol combined with sevoflurane anesthesia can accelerate the recovery of patients after cesarean section,and reduce oxidative stress and cognitive impairment of postoperative patients without significantly affecting the basic signs of patients.It has better anesthetic effect.
PropofolSevofluraneCesarean sectionQuality of awakeningOxidative stressCognitive function
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