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甲状腺功能亢进合并甲状腺癌的临床研究

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目的:探讨原发性甲状腺功能亢进症合并甲状腺乳头状癌的临床特点和病理特征.方法:回顾性分析2020年1月—2021年1月蚌埠医学院第一附属医院348例行甲状腺叶切除术且术中冰冻证实为甲状腺乳头状癌患者的临床病理资料,根据有无甲状腺功能亢进症分为A、B两组,收集病例数据分析并统计两组的临床病理特征.结果:两组患者中肿瘤直径≥1 cm在甲状腺癌患者比较,差异有统计学意义(χ2=5.538,P<0.05);在甲状旁腺及喉返神经功能损伤方面,B组发生率均高于A组,差异有统计学意义(χ2=4.891、4.172,P<0.05).结论:甲状腺功能亢进合并甲状腺癌患者通常会导致肿瘤明显增大,局部晚期发生率明显增高,增加患者术后并发症的出现,同时会对患者的预后产生影响,需要密切关注.
Clinical Study on Hyperthyroidism Combined with Thyroid Cancer
Objective:To explore the clinical and pathological characteristics of hyperthyroidism combined with papillary thyroid cancer.Methods:Retrospective collection of clinical and pathological data of 348 patients with thyroid papillary carcinoma who underwent thyroidectomy in the hospital from January 2020 to January 2021 and were confirmed by intraoperative freezing.They were divided into groups A and group B based on the presence or absence of hyperthyroidism.Case data was collected and analyzed to statistically analyze the clinical and pathological characteristics of the two groups.Results:There was statistically significant difference in thyroid cancer patients with≥1 cm hyperthyroidism between two groups(χ2=5.538,P<0.05).The incidence of parathyroid and recurrent laryngeal nerve injury in group B was higher than that in group A,and the difference was statistically significant(χ2=4.891,4.172;P<0.05).Conclusion:Patients with hyperthyroidism combined with thyroid cancer usually lead to significant tumor enlargement,with significant increase in the incidence of local advanced stage,an increase in postoperative complications,and an impact on the patient's prognosis,which requires close attention.

HyperthyroidismThyroid cancerClinical researchSurgical treatment

汤杰、翁文娟、姜芳倩、余小婷

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蚌埠医学院第一附属医院甲乳外科,安徽 蚌埠 233004

甲状腺功能亢进症 甲状腺癌 临床研究 外科治疗

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(16)