Analysis of the Influencing Factors and Management Strategies for Cancer-related Fatigue in Patients with Primary Liver Cancer Treated with Hepatic Artery Chemoembolization
Objective:To analyze the relevant factors and management strategies of cancer-related fatigue in patients with primary liver cancer treated with hepatic artery chemoembolization.Methods:A retrospective analysis was conducted on the clinical data of 115 patients with primary liver cancer who underwent hepatic artery chemoembolization from February 2021 to February 2023 in the hospital.The incidence of postoperative cancer-related fatigue was measured using the Piper Fatigue Revised Scale(PFS-R).Collecting data on the age,gender,and other factors of patients,and analyzing the impact and response factors of postoperative cancer-related fatigue.Results:Among 115 patients with primary liver cancer who underwent hepatic artery chemoembolization treatment,a total of 23 patients developed cancer-related fatigue after surgery,with an incidence rate of 20.00% (23/115).Univariate analysis showed that gender,age,educational level,history of hypertension,history of diabetes,and tumor stage were not related to cancer-related fatigue in patients with primary liver cancer after transcatheter arterial chemoembolization(TACE),and the difference was not statistically significant(χ2=0.078,0.009,2.266,0.038,0.079,0;P＞0.05).Living alone,monthly family income,payment method of medical expenses,degree of disease awareness,course of disease,adjuvant radiotherapy,and social support level are related to the occurrence of cancer-related fatigue in patients with primary liver cancer after hepatic artery chemotherapy and embolization treatment,and the difference is statistically significant(P＜0.05).The results of logistic regression analysis showed that living alone(OR=4.614),family monthly income＜5 000 yuan(OR=7.084),self funded medical expenses(OR=4.286),no awareness of the disease(OR=10.000),course of disease＞3 years(OR=7.389),with adjuvant radiotherapy(OR=5.856),and low social support level(OR=8.382)were the independent risk factors of the occurrence of cancer-related fatigue in patients with primary liver cancer after hepatic artery chemoembolization treatment(χ2=9.557,14.944,9.590,19.120,13.939,12.990,13.645;P＜0.05).Conclusion:Patients with primary liver cancer who undergo hepatic artery chemotherapy and embolization have a higher risk of developing cancer-related fatigue,which can be attributed to various factors such as living alone,having a monthly family income＜5 000 yuan,self funded medical expenses,lack of awareness of the disease,having adjuvant radiation therapy,and low levels of social support,etc.Therefore,clinical attention should be given to the high-risk groups mentioned above,and personalized management strategies should be implemented to ensure the physical and mental health of patients.
万方数据
维普
