Logistic Regression Analysis of Risk Factors Related to Cerebral Infarction in Patients with Hypertensive Intracerebral Hemorrhage Treated with Craniotomy Hematoma Clearance Surgery
Objective:To explore the relevant risk factors of cerebral infarction in patients with hypertensive intracerebral hemorrhage(HICH)after undergoing craniotomy hematoma removal surgery.Methods:The clinical data of 101 patients with HICH admitted to the hospital from January 2020 to December 2022 were retrospectively analyzed.All patients were treated with craniotomy hematoma removal.The patients were divided into the occurrence group and the non occurrence group according to the occurrence of cerebral infarction after surgery.The age,gender,time from onset to treatment,education level,course of hypertension,history of diabetes,history of hyperlipidemia,smoking and drinking history,preoperative Glasgow Scale(GCS),preoperative hematoma volume,brain edema volume,duration of intracranial pressure lowering medication use,and non-standard intraoperative procedures,were compared.Results:A total of 22 out of 101 patients developed cerebral infarction after surgery,with an incidence rate of 21.57%.There were statistically significant differences between the two groups in the course of hypertension,history of diabetes,history of hyperlipidemia,preoperative GCS score<8 points,preoperative hematoma volume≥40 mL,brain edema volume≥70 cm3,use time of intracranial pressure lowering drugs≥24 h,and non-standard operation(P<0.05).Logistic regression analysis showed that the duration of hypertension≥10 years(OR=5.108),history of diabetes(OR=3.567),history of hyperlipidemia(OR=3.903),preoperative GCS score<8 points(OR=3.315),preoperative hematoma volume≥40 mL(OR=7.350),brain edema volume≥70 cm3(OR=6.193),use time of intracranial pressure lowering drugs≥24 h(OR=29.500),and improper intraoperative procedures(OR=19.200)were high-risk factors for postoperative cerebral infarction in HICH patients(P<0.05,OR>1).Conclusion:The risk of postoperative cerebral infarction in patients with HICH is high,which is greatly influenced by the duration of hypertension≥10 years,history of diabetes,history of hyperlipidemia,preoperative GCS score<8 points,preoperative hematoma volume≥40 mL,brain edema volume≥70 cm3,use time of intracranial pressure lowering drugs≥24 h,and irregular operation during operation.Attention should be paid to early intervention of high-risk factors.
Hypertensive cerebral hemorrhageRemoval of craniotomy hematomaCerebral infarctionRisk factor