Systemic light amyloidosis is a progressive disease,which is caused by the misfolding of light chains of monoclonal immunoglobulin to form amyloid protein and deposited in multiple tissues and organs,leading to the destruction of tissue structure and organ dysfunction.When systemic amyloidosis affects the heart,it may be characterized by clinical heterogeneity,which is characterized by restrictive cardiomyopathy,refractory heart failure and arrhythmia,which may easily lead to missed diagnosis and misdiagnosis.The study reports 1 case of 40 year old middle-aged female who was diagnosed as systemic light chain myocardial amyloidosis due to the progressive aggravation of edema in both lower extremities and the discovery of serious cardiovascular events combined with serious multi system involvement.
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