Observation on the Effect of Non-invasive Positive Pressure Ventilation in the Treatment of Chronic Obstructive Pulmonary Disease with Type Ⅱ Respiratory Failure
Objective:To study the effects of non-invasive positive pressure ventilation on chronic obstructive pulmonary disease with type 11 respiratory failure.Methods:A total of 95 patients with chronic obstructive pulmonary disease(COPD)combined with type Ⅱ respiratory failures in the respiratory department of the hospital from Jan.2021 to Jan.2023 were included in this study,and they were divided into two groups with random number table.One group was consisted of 47 patients who received routine treatment and were determined as the control group.Another group of 48 cases treated with routine therapy combined with non-invasive positive pressure ventilation were designated as the observation group.Both groups of patients continued treatment for 2 weeks.Clinical efficacy,hospitalization time,hospitalization expenses,mechanical ventilation rate through tracheal intubation,blood oxygen saturation(SaO2),partial pressure of carbon dioxide(PCO2),partial pressure of oxygen(PO2),respiratory rate(RR),heart rate(HR),forced expiratory volume(FEVi)in the first second,forced vital capacity(FVC),and maximum peak expiratory flow rate(PEF)levels before and after treatment were compared.Results:The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(x2=5.207,P＜0.05).The hospitalization time of observation group was shorter than that of control group,and the hospitalization cost and tracheal intubation mechanical ventilation rate of observation group were lower than those of control group.The differences were statistically significant(t=9.514,4.923,x2=9.782,P＜0.05).After treatment,the levels of SaO2 and PO2 in observation group were higher than those in control group,while the levels of PCO2,RR and HR in observation group were lower than those in control group,with statistically significant difference(t=6.300,5.693,7.603,5.953,3.291;P＜0.05).After treatment,the levels of FEV1,FVC and PEF in observation group were higher than those in control group,with statistically significant difference(t=8.082,4.859,6.067;P＜0.05).Conclusion:Non invasive positive pressure ventilation can effectively shorten hospitalization time,reduce patients'economic burden,reduce the possibility of tracheal intubation mechanical ventilation,improve blood gas indicators and vital signs,improve lung function levels of patients with chronic obstructive pulmonary disease combined with type Ⅱ respiratory failure.
万方数据
维普
