黑龙江医学2024,Vol.48Issue(19) :2405-2408.DOI:10.3969/j.issn.1004-5775.2024.19.030

冠心病患者经皮冠状动脉介入术术后支架内再狭窄的相关影响因素及护理对策分析

Analysis of Influencing Factors of Stent Restenosis in Patients with PCI and Nursing Countermeasures

王燕 熊静静 马玉苗
黑龙江医学2024,Vol.48Issue(19) :2405-2408.DOI:10.3969/j.issn.1004-5775.2024.19.030

冠心病患者经皮冠状动脉介入术术后支架内再狭窄的相关影响因素及护理对策分析

Analysis of Influencing Factors of Stent Restenosis in Patients with PCI and Nursing Countermeasures

王燕 1熊静静 2马玉苗3
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作者信息

  • 1. 驻马店市中医院心脑血管内科,河南 驻马店 463000
  • 2. 驻马店市中医院心内科,河南 驻马店 463000
  • 3. 驻马店市中医院检验科,河南 驻马店 463000
  • 折叠

摘要

目的:了解冠心病患者经皮冠状动脉介入术(PCI)术后支架内再狭窄的相关影响因素,并制定针对性护理对策.方法:采用前瞻性队列研究方法对2020年2月—2022年2月驻马店市中医院收治的127例行PCI术治疗的冠心病患者进行为期12个月的研究,根据冠心病患者PCI术后支架内再狭窄发生情况将其分为发生组34例和未发生组86例.设计患者的基线资料表,纳入差异有统计学意义的变量,构建logistic回归模型,分析冠心病患者PCI术后支架内再狭窄的相关影响因素.结果:发生组患者长期吸烟、高血压及高脂血症占比高于未发生组,差异有统计学意义(x2=8.825、9.093、15.602、P<0.05);发生组患者同型版月光氨酸(Hcy)、白细胞介素(IL)-18水平均高于未发生组,差异均有统计学意义(t=8.930、7.553,P<0.05);logistic回归分析结果显示,长期吸烟、高血压、高脂血症、Hcy水平过表达及IL-18水平过表达是冠心病患者PCI术后支架内再狭窄的影响因素,差异均有统计学意义(OR>1,P<0.05).结论:冠心病患者PCI术后支架内再狭窄的发生风险偏高,长期吸烟、高血压、高脂血症、Hcy水平过表达及IL-18水平过表达是冠心病患者PCI术后支架内再狭窄的影响因素,可根据上述影响因素采取针对性预防措施,以规避PCI术后支架内再狭窄的发生风险.

Abstract

Objective:To know the relevant influencing factors of stent restenosis after percutaneous coronary intervention(PCI)in patients with coronary heart disease,and to develop targeted nursing strategies.Methods:A prospective cohort study was used to conduct a 12 month prospective cohort study on 127 patients with coronary heart disease who underwent PCI in the hospital from February 2020 to February 2022.According to the incidence of in stent restenosis in patients with coronary heart disease after PCI,they were divided into an occurrence group and a non occurrence group.At the same time,a patient baseline data table was designed,and statistically significant variables were included to construct a logistic regression model.The relevant influencing factors of stent restenosis in patients with coronary heart disease after PCI was analyzed.Results:Single-factor analysis showed that the proportion of long-term smoking,hypertension,and hyperlipidemia in patients with coronary heart disease in the occurrence group was higher than that in the non occurrence group,with statistically significant difference(x2=8.825,9.093,15.602;P<0.05).The levels of Hcy and IL-18 in patients with coronary heart disease in the occurrence group were higher than those in the non occurrence group,with statistically significant difference(t=8.930,7.553;P<0.05).After constructing a logistic regression model,the analysis results showed that long-term smoking,hypertension,hyperlipidemia,serum Hcy overexpression,and serum IL-18 overexpression were the influencing factors for stent restenosis in patients with coronary heart disease after PCI(OR>1,P<0.05).Conclusion:The risk of stent restenosis after PCI for coronary heart disease is relatively high.Long term smoking,hypertension,hyperlipidemia,serum HCY overexpression,and serum IL-18 overexpression are influencing factors for stent restenosis in patients with coronaiy heart disease after PCI.Clinical prevention measures should be taken according to the above factors to avoid the risk of intrastent restenosis after PCI.

关键词

冠心病/经皮冠状动脉介入术/支架内再狭窄/影响因素

Key words

Coronary heart disease/Percutaneous coronary intervention/Restenosis within the stent/Influencing factor

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出版年

2024
黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
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