首页|狼疮性肾炎患者伴肾功能异常的高危因素及护理干预措施分析

狼疮性肾炎患者伴肾功能异常的高危因素及护理干预措施分析

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目的:探讨狼疮性肾炎(LN)患者伴肾功能异常的高危因素及护理干预措施.方法:选取2020年8月—2022年8月郑州大学第一附属医院收治的125例LN患者作为研究对象,根据肾小球滤过率将其分为肾功能正常组66例(≥90 mL/min)和肾功能异常组59例(<90 mL/min),收集两组患者的基础资料,采用logistic回归分析,获得影响LN患者伴肾功能异常的高危因素.结果:125例LN患者中,59例肾功能异常,发生率为47.20%.病程≥10个月、合并高血压、合并糖尿病、合并感染、狼疮活动程度中度及重度、合并贫血、合并低蛋白血症是影响LN患者肾功能异常的高危因素,差异均有统计学意义(P<0.05,OR>1).结论:病程≥10个月、合并高血压、合并糖尿病、合并感染、狼疮活动程度中度及重度、合并贫血、合并低蛋白血症是影响LN患者肾功能异常的高危因素,应早期识别并加以干预,防止肾功能持续损伤.
Analysis of High-risk Factors and Nursing Intervention Measures for Lupus Nephritis Patients With Renal Dysfunction
Objective:To investigate the risk factors and nursing interventions of patients with lupus nephritis(LN)with abnormal renal function.Methods:125 patients with LN admitted to the hospital from August 2020 to August 2022 were selected and divided into normal renal function group(≥90 mL/min)and abnormal renal function group(<90 mL/min)according to the glomerular filtration rate.Basic data of the two groups were collected,and logistic regression analysis was carried out to obtain the risk factors for renal dysfunction in LN patients.Results:Among 125 patients with LN,59 cases had abnormal renal function(47.20%).That the course of disease ≥ 10 months,combined with hypertension,combined with diabetes,combined with infection,moderate OR severe lupus activity,combined with anemia and combined with hypoproteinemia were high risk factors for renal dysfunction in LN patients(P<0.05,OR>1).Conclusion:Patients with LN have a high risk of renal dysfunction,which is closely related to the course of disease ≥ 10 months,combined hypertension,combined diabetes,combined infection,moderate or severe lupus activity,combined anemia and combined hypoproteinemia.These high-risk factors should be identified as early as possible,and targeted nursing intervention should be carried out to protect renal function.

Lupus nephritisAbnormal renal functionInfluencing factorsNursing measures

孔祥红

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郑州大学第一附属医院入院接诊处,河南 郑州 450000

狼疮性肾炎 肾功能异常 影响因素 护理措施

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(20)