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T2DM合并代谢相关脂肪性肝病诊断及治疗的研究进展

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2型糖尿病(T2DM)与代谢相关脂肪性肝病(MAFLD)具有相似的发病机制,两者相互影响、互为因果,早期诊断MAFLD并进行及时干预对于改善糖尿病患者预后具有重要临床意义.目前,临床诊断MAFLD方法仍局限于影像学技术及现有生物学标志物,且临床应用存在一定局限性,对于MAFLD的治疗目前无特效药物,临床仍以生活方式干预和体育锻炼为主要治疗手段,降糖药物和减肥手术对于T2DM合并MAFLD有一定临床获益,但仍需更多临床数据支持.因此文章就近几年T2DM合并MAFLD的诊断及治疗相关研究进展进行综述.
Research Progress in the Diagnosis and Treatment of Type 2 Diabetes Mellitus with Metabolic Associated Fatty Liver Disease
Type 2 diabetes mellitus and metabolic associated fatty liver disease have the similar pathogenesis,and they influence each other and have reciprocal causation.Early diagnosis of MAFLD and timely intervention are of great clinical significance for improving the prognosis of diabetic patients.At present,there are certain limitations in the clinical diagnosis of MAFLD because it is still limited to the imaging techniques and existing biological markers.There is currently no specific drugs for the treatment of MAFLD,lifestyle intervention and physical exercise are still the main treatments.Hypoglycemic drugs and bariatric surgery have certain clinical benefits for T2DM combined with MAFLD,but more clinical data is needed.Therefore,the study reviews the research progress on the diagnosis and treatment of T2DM combined with MAFLD in recent years.

MAFLDT2DMDiagnosisTreatment

杨艳琳、王超

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陆军第七十八集团军医院内二科,黑龙江 牡丹江 157000

陆军第七十八集团军医院质量管理科,黑龙江 牡丹江 157000

代谢相关脂肪性肝病 2型糖尿病 诊断 治疗

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(20)