Effect of Shenling Baizhu Powder Combined with Western Medicine Treatment on Microinflammatory Status and Anemia in Chronic Renal Failure Hemodialysis Patients
Objective:To explore the effect of Shenling Baizhu Powder combined with Western medicine treatment on micro inflammatory status and anemia in hemodialysis patients with chronic renal failure(CRF).Methods:80 CRF patients who underwent hemodialysis treatment in the hospital from May 2021 to February 2023 were randomly divided into two groups by random number table method,with 40 patients in each group.The control group was treated with western medicine,while the observation group was treated with modified Shenling Baizhu Powder.The clinical efficacy,micro inflammatory status,anemia status,immune function,traditional Chinese medicine syndrome scores,and adverse reactions between the two groups were compared.Results:The total clinical efficacy rate of the observation group was lower than that of the control group(x2=6.275,P＜0.05).The levels of tumor necrosis factor α(TNF-α),interleukin-6(IL-6)and C-reactive protein(CRP)in observation group were lower than those in control group,with statistically significant difference(t=6.738,4.301,3.817;P＜0.05).After treatment,the levels of hemoglobin(Hb),erythrocyte specific volume(Hct)and erythrocyte(RBC)in observation group were higher than those in control group,with statistically significant difference(t=11.930,8.109,13.395;P＜0.05).After treatment,CD4+,CD4+/CD8+levels in observation group were higher than those in control group,and CD8+levels were lower than those in control group,with statistically significant difference(t=12.158,2.095,4.064;P＜0.05).After treatment,patients in the observation group were lower than those in the control group in fatigue,white face,shortness of breath,lazy speech,lumbago and knee weakness and little food,with statistically significant difference(t=5.597,4.991,8.474,8.340,7.057;P＜0.05).No adverse reactions occurred in both groups.Conclusion:The combination of western medicine and Shenling Baizhu Powder can improve the micro inflammatory state,anemia status,and immune function of CRF hemodialysis patients;and alleviate clinical symptoms.It is a safe and effective treatment plan.
Chronic renal failureHemodialysisAddition and subtraction of Shenling Baizhu PowderMicro inflammatory stateAnemia statusImmunologic function
万方数据
维普
