首页|血清尿酸联合中心静脉-动脉血二氧化碳分压差对急性心肌梗死患者近期心源性休克的预测价值

血清尿酸联合中心静脉-动脉血二氧化碳分压差对急性心肌梗死患者近期心源性休克的预测价值

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目的:探讨血清尿酸(UA)联合中心静脉-动脉血二氧化碳分压差(Pcv-aCO2)对急性心肌梗死(AMI)患者近期心源性休克(CS)的预测价值.方法:选取2021年1月—2022年12月商丘市第一人民医院收治的250例经皮冠状动脉介入术(PCI)的AMI患者作为研究对象,根据术后1个月是否发生CS将其分为休克组32例和非休克组218例.比较两组患者血清UA水平和Pcv-aCO2,分析AMI患者近期CS的危险因素和血清UA、Pcv-aCO2对AMI患者近期CS的预测价值.结果:休克组患者白细胞计数(WBC)、尿素氮(BUN)、肌酐(Cr)、C反应蛋白(CRP)、N末端B型利钠肽原(NT-proBNP)、血清UA水平及Pcv-aCO2均高于非休克组患者,差异均有统计学意义(t=3.224、4.098、3.938、2.753、4.212、4.644、8.443,P<0.05).WBC、BUN、Cr、CRP、NT-proBNP、血清UA、Pcv-aCO2是AMI患者近期CS的危险因素.血清UA联合Pcv-aCO2预测AMI患者近期CS的灵敏度高于各指标单独预测,差异均有统计学意义(Z=2.154、2.128,P<0.05),其特异度与各指标单独预测基本一致.结论:血清UA和Pcv-aCO2是AMI患者近期CS的危险因素,二者联合对AMI患者近期CS具有良好的预测价值.
Predictive Value of Serum UA Combined with Pcv-aCO2 on Short-term Cardiogenic Shock in Patients with Acute Myocardial Infarction
Objective:To explore the predictive value of serum uric acid(UA)combined with central veno-arterial partial pressure difference of carbon dioxide(Pcv-aCO2)for short-term cardiogenic shock(CS)in patients with acute myocardial infarction(AMI).Methods:250 AMI patients were selected as the study subjects and divided into shock group and non-shock group based on the occurrence of CS,and the serum UA level and Pcv-aCO2 of the two groups were compared.The risk factors for short-term CS in AMI patients and the predictive value of serum UA and Pcv-aCO2 for short-term CS in AMI patients were analyzed.Results:The white blood cell count(WBC),urea nitrogen(BUN),creatinine(Cr),C-reactive protein(CRP),N-terminal B-type natriuretic peptide(NT-proBNP),UA level and Pcv-aCO2 in shock group were higher than those in non-shock group.The differences were statistically significant(t=3.224,4.098,3.938,2.753,4.212,4.644,8.443;P<0.05).WBC,BUN,Cr,CRP,NT-proBNP,serumUA,Pcv-aCO2 were the risk factors for CS in patients with AMI.The sensitivity of serum UA combined with Pcv-aCO2 to predict the near-term CS in AMI patients was higher than that predicted by each indicator alone,and the differences were statistically significant(Z=2.154,2.128;P<0.05),and the specificity was basically consistent with that predicted by each indicator alone.Conclusion:Serum UA level and Pcv-aCO2 are risk factors for CS in patients with AMI,and their combination has good predictive value for CS in patients with AMI.

SERUM uric acidCentral veno-arterial carbon dioxide partial pressure differenceAcute myocardial infarctionCardiogenic shock

李颖、卢少玲

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商丘市第一人民医院心脏重症监护室,河南 商丘 476100

血清尿酸 中心静脉-动脉血二氧化碳分压差 急性心肌梗死 心源性休克

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(24)