Spontaneous subarachnoid hemorrhage is a common hemorrhagic stroke disease,which has a high disability rate and mortality rate,bringing significant burden to society and families.The post-hemorrhage physiological mechanisms are complex,leading to changes such as neuronal edema,blood-brain barrier permeability alteration,and cerebral vasospasm.Extensive basic experimental studies have found that blood toxicity,inflammatory lesions,mitochondrial death,and free radical release all participate in this process of change.The study elucidates the pathological physiological mechanisms and apoptotic pathways after spontaneous subarachnoid hemorrhage to provide potential targets or strategies for treating patients with subarachnoid hemorrhage.
Spontaneous subarachnoid hemorrhageApoptosisPhysiological and physiological mechanisms diseaseTreatment