首页|补肺养心方治疗慢性肺源性心脏病失代偿期临床疗效观察

补肺养心方治疗慢性肺源性心脏病失代偿期临床疗效观察

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目的:分析补肺养心方治疗慢性肺源性心脏病失代偿期的临床疗效.方法:收集我院2020 年2 月至 2022 年 2月符合纳入标准的慢性肺源性心脏病失代偿期 120 例合格受试者,采用简单随机的方法,设立为治疗组(中药汤剂联合西医治疗)和对照组(西医常规治疗组),两组各 60 例患者.比较两组临床疗效、中医证候积分、心功能(双侧房室内径、PASP、LVEF、LVDF、RVEF)、血清指标(NT-proBNP).结果:治疗组完全控制率(58.33%)高于对照组(36.67%),差异有统计学意义(P<0.05),两组总有效率比较,差异无统计学意义(P>0.05);治疗组中医证候积分低于对照组,差异有统计学意义(P<0.05);治疗组双侧房室内径、PASP、NT-proBNP低于对照组,LVEF、LVDF、RVEF高于对照组,差异有统计学意义(P<0.05).结论:补肺养心方控制CPHD患者临床症状的效果明显,有助于改善患者心功能.
Clinical Observation on the Efficacy of Bufei Yangxin Formula in Treating Chronic Pulmonary Heart Disease in the Decompensated Stage
Objective:To analyze the clinical efficacy of Bufei Yangxin Formula in treating chronic pulmonary heart disease during the decompensated period.Methods:Collect 120 eligible subjects of chronic pulmonary heart disease who met the inclusion criteria from February 2020 to February 2022 in our hospital during the decompensated period.Using a simple randomized method,they were divided into a treatment group (traditional Chinese medicine decoction combined with Western medicine treatment)and a control group (conventional Western medicine treatment group),with 60 patients in each group.Compare the clinical efficacy,traditional Chinese medicine syndrome scores,cardiac function (bilateral atrioventricular diameter,PASP,LVEF,LVDF,RVEF),and serum indicators (NT proBNP)between the two groups.Results:The complete control rate in the treatment group (58.33%)was higher than that in the control group (36.67%),with a statistically significant difference(P<0.05).There was no statistically significant difference in the total effective rate between the two groups(P>0.05 );The traditional Chinese medicine syndrome score in the treatment group was lower than that in the control group,and the difference was statistically significant(P<0.05);The bilateral atrioventricular diameter,PASP,and NT proBNP in the treatment group were lower than those in the control group,while LVEF,LVDF, and RVEF were higher than those in the control group,with statistically significant differences(P<0.05).Conclusion:The effect of Bufei Yangxin Formula on controlling clinical symptoms of CPHD patients is significant,which helps to improve their heart function.

Chronic pulmonary heart diseasePeriod of loss of compensationBufei Yangxin FormulaLung functionCardiac function

刘立蓁、曾冬青

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赣县区人民医院 超声科(江西 赣州 341100)

慢性肺源性心脏病 失代偿期 补肺养心方 肺功能 心功能

赣州市科技计划项目

GZ2023ZSF370

2024

黑龙江医药
黑龙江省药品审评认证中心

黑龙江医药

影响因子:0.597
ISSN:1006-2882
年,卷(期):2024.37(1)
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