Objective:To explore the evaluation of urinary microalbumin (mAlb),glycosylated hemoglobin (HbA1c)and cystatin C (Cys-C)in early diagnosis of diabetes nephropathy on early renal injury.Methods:From July 2021 to December 2022,90 patients with diabetes who were treated in Xinfeng County People's Hospital of Jiangxi Province were selected as the research objects.Among them,simple diabetes was recorded as group A (30 cases),early renal injury was recorded as group B (30 cases),and diabetes nephropathy was recorded as group C (30 cases);30 healthy individuals who underwent physical examinations during the same period were included in the control group.The levels of mAlb,HbA1c and Cys-C in the four groups were compared,and the positive detection rates of mAlb,HbA1c and Cys-C in the four groups were analyzed.Results:The levels of mAlb,HbA1c,and Cys-C in groups A,B,and C were all higher than those in the control group(P<0.05).And group C>group B>group A(P<0.05).The positive rates of mAlb,HbA1c,and Cys-C in groups A,B,and C were higher than those in the control group(P<0.05).And group C>group B>group A(P<0.05).According to ROC curve analysis,the combined detection of AUC by mAlb,HbA1c,and Cys-C showed higher sensitivity and specificity than single detection(P<0.05).Conclusion:The combined detection of mAlb,HbA1c and Cys-C can improve the positive detection rate of early renal injury in patients with diabetes nephropathy,and is conducive to reflecting the severity of early renal injury.
维普
万方数据
