Objective:To investigate the curative effect of Guishao Dihuang Decoction on acute stage of peripheral facial paralysis.Methods:From May 2021 to May 2022,60 patients with acute peripheral facial paralysis were selected and randomly divided into control group and observation group,with 30 cases in each group.Both groups were given routine acupuncture treatment,and observation group was treated with Guishao Dihuang Decoction on this basis.The treatment effect,TCM syndrome score,facial nerve function score,quality of life change and adverse reactions of facial paralysis were compared between the two groups.Results:Compared with the control group,the effective rate of the observation group was higher(P<0.05).Compared with before treatment,TCM syndrome score decreased and H-B score increased in both groups after treatment.TCM syndrome score in observation group was lower than that in control group,and H-B score was higher than that in control group(P<0.05).Compared with before treatment,after treatment,the scores of physical function in the FDI scores of both groups increased,and the scores of social life function decreased.The scores of physical function in the observation group were higher than those in the control group,but the scores of social life function were lower than those in the control group(P<0.05).There was no significant difference in adverse reactions between the two groups(6.67%VS 10.00%,P=0.640).Conclusion:Guishao Dihuang Decoction in acute stage of peripheral facial paralysis has better effect,symptoms and facial nerve function can be better improved,the patients'physical function and social life quality are better,and the adverse reactions are less,which has certain clinical application value.