Predictive Value of Serum Prealbumin Combined with Interleukin-6 in Children with Asthmatic Bronchitis
Objective:Exploring the predictive value of the combined detection of serum prealbumin and interleukin-6(IL-6)levels for pediatric asthmatic bronchitis,providing a basis for early prevention and treatment of asthmatic bronchitis in children.Methods:Selecting 100 children with bronchitis at Ganzhou People's Hospital from August 2021 to September 2022 as the research subjects,they were divided into a wheezing group and a non wheezing group of 50 cases each based on their concurrent wheezing situation.Enzyme linked immunosorbent assay was used to detect the serum prealbumin and IL-6 levels of the two groups of children,analyze the collected data,draw receiver operating curve(ROC)curves,and analyze the predictive value of serum prealbumin and IL-6,as well as their combined detection,for pediatric wheezing bronchitis.Results:The expression level of serum prealbumin in the wheezing group was lower than that in the non wheezing group,and the difference was statistically significant(P＜0.05).The expression level of serum IL-6 was higher than that in the non wheezing group,and the difference was statistically significant(P＜0.05).The ROC curve results showed that the combined detection of serum prealbumin and IL-6 predicted an AUC of 0.988 for children with concurrent asthma,which was higher than 0.858 for serum prealbumin and 0.878 for IL-6,with higher sensitivity and specificity than single detection.Conclusion:The level of serum prealbumin in children with asthmatic bronchitis decreased,and the level of serum IL-6 expression increased.The two combined detection has high clinical value in early diagnosis of asthmatic bronchitis,and is worth popularizing.
万方数据
维普
