首页|超声引导下微创灌洗联合中医治疗非哺乳期乳腺炎的临床研究

超声引导下微创灌洗联合中医治疗非哺乳期乳腺炎的临床研究

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目的:探讨超声引导下微创灌洗联合中医治疗非哺乳期乳腺炎(NPM)的临床效果.方法:选取赣州市南康区第一人民医院2021年9月—2023年8月期间收治的NPM(脓肿期)患者60例,按随机数字表法分为两组,各30例.对照组采取小切口切开排脓0.1%乳酸依沙吖啶溶液纱条填塞引流换药+头孢克洛胶囊联合甲泼尼龙片治疗,观察组采取超声引导下微创灌洗联合中药内服外用治疗,为期6周.对比两组临床疗效、炎性因子水平[C反应蛋白(CRP)、白介素-6(IL-6)]、免疫指标[免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、免疫球蛋白(IgM)]、脓肿持续时间及疾病复发率.结果:观察组治疗总有效率为100.00%,高于对照组的80.00%,差异有统计学意义(P<0.05).术后1周,观察组CRP、IL-6水平低于对照组,IgA、IgG、IgM水平高于对照组,差异有统计学意义(P<0.05);观察组脓肿持续时间短于对照组,差异有统计学意义(P<0.05);观察组疾病复发率低于对照组,但差异无统计学意义(P>0.05).结论:超声引导下微创灌洗联合中医治疗NPM(脓肿期)的疗效确切,可以加快脓肿消退,抑制炎症反应,调节机体免疫,降低复发率.
Clinical Study of Ultrasound-Guided Minimally Invasive Irrigation Combined with Traditional Chinese Medicine in the Treatment of Non-Lactation Mastitis
Objective:To explore the clinical effect of ultrasound-guided minimally invasive lavage combined with traditional Chinese medicine for non puerperal mastitis(NPM).Methods:A total of 60 patients with NPM(abscess stage)admitted to the First People's Hospital of Nankang District,Ganzhou City from September 2021 to August 2023 were divided into two groups with 30 patients in each group according to random number table method.The control group was treated with a small incision and drainage of 0.1%ethacridine lactate solution with gauze packing,drainage and dressing change+cefaclor capsule combined with methylprednisolone tablet;the observation group was treated with ultrasound-guided minimally invasive irrigation combined with Chinese medicine for internal and external use for 6 weeks.The clinical efficacy,inflammatory factor levels[C-reactive protein(CRP),interleukin-6(IL-6)],immune indexes[immunoglobulin A(IgA),immunoglobulin G(IgG),immunoglobulin(IgM)],duration of abscess and disease recurrence rate were compared between the two groups.Results:The total effective rate of observation group was 100.00%,higher than that of control group 80.00%,the difference was statistically significant(P<0.05).One week after surgery,the levels of CRP and IL-6 in observation group were lower than those in control group,while the levels of IgA,IgG and IgM were higher than those in control group,with statistical significance(P<0.05).The duration of abscess in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05).The recurrence rate of the observation group was lower than that of the control group,but the difference was not statistically significant(P>0.05).Conclusion:Ultrasound-guided minimally invasive irrigation combined with traditional Chinese medicine is effective in the treatment of NPM(abscess stage),which can accelerate the regression of abscess,inhibit the inflammatory response,regulate the immune system and reduce the recurrence rate.

Non-lactation mastitisUltrasound-guided minimally invasive irrigationTraditional Chinese medicine treatmentInflammatory responseImmune functionRecrudescence

黄小莉、吴桂健、黄小琴

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赣州市南康区第一人民医院功能科(江西南康 341400)

赣州市南康区第一人民医院普外科(江西南康 341400)

赣州市南康区中医院检验科(江西 南康 341400)

非哺乳期乳腺炎 超声引导下微创灌洗 中医治疗 炎症反应 免疫功能 复发

赣州市指导性科技计划项目

GZ2023ZSF499

2024

黑龙江医药
黑龙江省药品审评认证中心

黑龙江医药

影响因子:0.597
ISSN:1006-2882
年,卷(期):2024.37(5)
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