Objective:To investigate the effects of unilateral pedicle screw fixation on immune function and long-term functional recovery in patients with acute spinal trauma.Methods:80 patients with acute spinal trauma admitted to our hospital from October 2021 to February 2024 were selected as the study subjects.They were randomly divided into two groups using a random number table method.The control group received traditional bilateral pedicle screw internal fixation surgery,while the observation group received u-nilateral pedicle screw internal fixation surgery through the injured vertebra.The surgical effects,immune function,and postoperative adverse events of the two groups of patients were compared.Results:The observation group(surgery,bed rest,hospitalization)had lower time and intraoperative bleeding compared to the control group(P＜0.05);There were significant differences in postoperative cortisol(Cor),adrenocorticotropic hormone(ACTH),anterior vertebral height compression ratio,and Cobb angle of vertebral kyphosis between the observation group and the control group(P＜0.05);The postoperative immune function indicators such as CD3+,CD4+,CD4+/CD8+in the observation group were significantly higher than those in the control group(P＜0.05);The incidence of postoperative adverse events in the observation group was lower than that in the control group(P＜0.05).Conclusion:U-nilateral pedicle screw internal fixation of the injured vertebra can not only improve the surgical effect,but also have a smaller impact on the immune function of patients with acute spinal trauma,which is more conducive to long-term spinal function recovery and is worth promoting.
关键词
经伤椎单侧椎弓根螺钉内固定术/急性脊柱创伤/围术期指标/手术效果/免疫功能
Key words
Unilateral Pedicle Screw Fixation Through Injured Vertebra/Acute Spinal Trauma/Perioperative Indexes/Operation Effect/Immune Function
维普
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