Analysis of Risk Factors of Small Cerebral Vascular Disease in Patients with Ischemic Stroke
Objective:To explore the risk factors of small cerebral vascular disease in patients with ischemic stroke.Methods:The clinical data of 300 patients with ischemic stroke admitted to our hospital were retrospectively selected and divided into two groups(n=215 cases)with and without small cerebral vascular disease(n=85 cases).The groups were divided according to whether the patients had small cerebral vascular disease,and the cases were selected from February 2020 to February 2023.The clinical data of all patients were collected,and the prognosis of the two groups was analyzed by multivariate Logistic regression analysis.The risk factors of small cerebral vascular disease(patients with ischemic stroke)were analyzed.Results:Univariate and multivariate Logistic regression analysis showed that Age,hypertension,diabetes,and high serum homocysteine(HCY)and uric acid(UA)levels were independent risk factors for ischemic stroke in patients with small cerebral vascular disease(OR=2.192,2.321,2.145,2.487,2.168,P<0.05).Two groups of patients had significantly lower NIHSS scores on the 7th day of admission compared to those at reduced admission(P<0.05)on the National Institutes of Health Stroke Scale;And compared between groups,the NIHSS score on the 7th day after admission and the modified Rankin score(mRS score)on the 90th day after treatment in the group with concomitant cerebral small vessel disease were also higher than those in the group without concomitant cerebral small vessel disease(P<0.05).Conclusion:Compared with patients with ischemic stroke,the prognosis of patients with ischemic stroke complicated with small cerebral vascular disease is worse.Older age,complicated with hypertension,complicated with diabetes,and high serum HCY and UA levels are independent risk factors for ischemic stroke.Therefore,according to the above conclusions,targeted prevention and treatment measures can be given to patients with ischemic stroke complicated with small cerebral vascular disease to reduce the risk of ischemic stroke.