The effect of nutritional intervention based on prognostic nutritional index on gastrointestinal hormone levels and nutritional status in patients with decompensated hepatitis B cirrhosis
The effect of nutritional intervention based on prognostic nutritional index on gastrointestinal hormone levels and nutritional status in patients with decompensated hepatitis B cirrhosis
Objective:To analyze the effect of nutritional intervention based on the prognostic nutritional index(PNI)on gastrointestinal hormone levels and nutritional status in patients with decompensated hepatitis B cirrhosis(DHBC).Methods:Clinical data of 87 patients with hepatitis B DHBC admitted to the Third People's Hospital of Zhengzhou from October 2021 to October 2023 were collected and divided into two groups based on different nursing intervention models.The control group(42 patients)received routine nursing intervention,while the observation group(45 patients)received PNI-based nutritional intervention in addition to the routine nursing provided to the control group.The levels of gastrointestinal hormones(motilin and gastrin),nutritional status[serum albumin(ALB),transferrin(TRF),total protein(TP),hemoglobin(Hb)],liver function[serum aspartate aminotrans-ferase(AST),total bilirubin(TBil),alanine aminotransferase(ALT)],and quality of life[chronic liver disease questionnaire(CLDQ)]were compared between the two groups before and after the intervention.Results:After the intervention,the levels of motilin and gastrin decreased in both groups,with lower levels observed in the obser-vation group compared to the control group(P＜0.05).The levels of serum ALB,TRF,TP and Hb increased in both groups after the intervention,with a more significant increase observed in the observation group(P＜0.05).The levels of serum AST,TBil and ALT were lower in the observation group compared to the control group after the intervention(P＜0.05).The quality of life improved in both groups after the intervention,and the scores of each dimension of CLDQ were higher in the observation group compared to the control group(P＜0.05).Conclusion:Nutritional intervention based on the PNI for patients with DHBC can improve gastrointestinal hormone levels,nutri-tional status,liver function,and promote an improvement in quality of life.
维普
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