Application of plain Scan CT in the diagnosis of tuberous sclerosis complex in children
Objective:To investigate the diagnostic efficacy of plain scan CT in pediatric tuberous sclerosis complex.Methods:80 pediatric patients with tuberous sclerosis complex treated at the Department of Radiology,Kaifeng Children's Hospital,from January 2019 to January 2022,were selected as study subjects to analyze the di-agnostic efficacy.Results:Among the 80 tuberous sclerosis complex cases examined by plain scan CT,78 showed subependymal calcified nodules(with varying sizes of calcifications and high boundary clarity).Of these,71 nod-ules were located in the lateral walls of lateral ventricles,4 in the lateral walls of the third ventricle,and 3 in the lateral walls of the fourth ventricle.There were 72 multiple lesions and 6 isolated calcified nodules.Additionally,41 cases presented with cortical or subcortical nodules,manifested as low-density lesions predominantly in a patchy shape.20 cases exhibited patchy calcifications within the brain parenchyma,and 17 showed ventricular sys-tem enlargement(mild enlargement of bilateral lateral ventricles in 12 cases and significant enlargement of lateral ventricles or combined with enlargement of the third ventricle in 5 cases).Enhanced CT scans in 3 cases revealed nodular enhancement in the distal ventricular wall.In cranial CT diagnoses,3 cases exhibited overlapping calcified nodules resembling a candle-wax drip pattern,and 1 case showed patchy low-density lesions in the cerebral cor-tex.In lung CT diagnoses,4 cases had multiple nodules in the lung parenchyma,and 2 cases presented with spon-taneous pneumothorax.Renal CT diagnoses revealed 4 cases with enlarged renal contours and 2 cases with masses accompanied by hemorrhage.In liver CT diagnoses,5 cases showed multiple fatty density masses within the hepatic system.Thoracic CT diagnoses identified 3 cases with multiple speckled and plaque-like sclerotic nodules in tho-racic vertebral bodies and their annexes.Conclusion:Plain scan CT can detect intracranial calcified or high-den-sity nodules in patients with tuberous sclerosis complex,thereby demonstrating its high clinical diagnostic value.
childrentuberous sclerosis complexCT diagnosissubependymal calcified nodulescortical or subcortical nodules
万方数据
维普
