[Objective] The aim was to study the anti-bacterial effects of 5 kinds of Chinese herb extracts on Ameromonas hydrophila in vitro. [Method] in vitro anti-bacterial effects of 5 kinds of Chinese herb extracts like Galla Chinensis, Syzygium aromaticum, Salvia miltiorrhiza, Punica granatum L. and Terminalia chebula Retz on Ameromonas hydrophila were studied; furthermore, cure rates of the Chinese herb extracts with better anti-bacterial effects were determined to find out the optimal drug dosage. [Result] Under the same experimental conditions, Galla Chinensis, Punica granatum and Terminalia chebula Retz had relatively strong anti-bacterial effects on Ameromonas hydrophila, among them the anti-bacterial effect of Galla Chinensis was significantly higher than those of the others (P<0.05). The optimal treatment dose of Galla Chinensis treating bacterial septicemia caused by Aeromonas hydrophila was that they were treated with medicated bath for 40 min by 0.5 mg/ml Galla Chinensis extract, and the cure rate was 100%. [Conclusion] The research provides a scientific drug basis for the control and prevention of outbreak bacterial diseases of fish.
Chinese medicinal herbGalla ChinensisAmeromonas hydrophilaAnti-bacterial effectCure rate