Optimization of the Formula of Maca Lozenges by Orthogonal Test
The orthogonal experimental design was used to optimize the formula of maca lozenge and explore the preparation techniques and product property of maca lozenges.With the sensory evaluation of maca lozenge as the indicator,L16 (44) orthogonal design graph was used to select the optimal techniques,and to investigate the stability,heavy metals and microorganisms contents in the tablets.The optimal formula was 80％ of maca power,12％ of Rhodiola rosea powder,and 6％ of Angelica sinensis powder,where the comprehensive sensory index reached 246.Moreover,under the optimal conditions,various kinds of heavy metals contents were in consistent with the GB164740 standards,and there was no significant change in color,size,friability,and disintegration time,as well as microorganism content during the 12-month preservation.With simple,easy and reliable technique and quality control method,the process study had obtained the national patent process (patent number:ZL200810233796.X),and the contents of heavy metals and microorganisms laid foundation for the quality standard.
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