Analysis of relationship between ultrasound image characteristics and clinicopathology and TCM syndrome type distribution in patients with granulomatous mastitis in mass stage
Analysis of relationship between ultrasound image characteristics and clinicopathology and TCM syndrome type distribution in patients with granulomatous mastitis in mass stage
Objective To explore the relationship between ultrasound image characteristics and clinicopathological staging and TCM syndrome type distribution in patients with granulomatous mastitis(GLM)in mass stage.Methods 56 patients with GLM in mass stage in the hospital were retrospectively selected from August 2022 to August 2023 and included in mass stage group.In addition,30 patients with GLM in non-mass stage(abscess stage,post-ulcer stage)during the same time period were selected and enrolled as non-mass stage group.All patients underwent Doppler ultrasonography and were confirmed by pathol-ogy.The differences in ultrasound image characteristics(lesion size,shape,boundary,echo,calcification,catheter dilatation,blood flow signal)between the two groups were compared,and the relationship between ultrasound image characteristics and GLM in mass stage was analyzed by multivariate regression model.According to TCM syndrome types and tongue pulse condi-tions,the patients were divided into four syndromes:liver depression and phlegm coagulation syndrome,liver-stomach stagna-tion heat syndrome,phlegm-blood stasis blocking syndrome and yang deficiency and phlegm coagulation syndrome.The differ-ences in ultrasound image characteristics were compared among patients with GLM in mass stage of different syndrome types.Results The proportions of lesions<6 cm,clear boundary,uniform echo,no calcification,no catheter dilatation and blood flow signal grade 0-I in mass stage group were significantly higher than those in non-mass stage group.Multivariate regres-sion analysis showed that no catheter dilatation and blood flow signal grade 0-I were independent risk factors for GLM in mass stage.There was a statistically significant difference in the blood flow signal of ultrasound image among patients with different syndrome types of GLM in mass stage.The number of cases with blood flow signal grade 0-I in yang deficiency and phlegm coagulation syndrome(6 cases,75.00%)was the highest,and the liver-stomach stagnation syndrome(2 cases,12.50%)was the lowest.Conclusion The ultrasound image characteristics of lesion size,boundary,echo,calcification,catheter dilatation and blood flow signal in patients with different stages of GLM are different.Ultrasound images show that no catheter dilatation and blood flow signal grade 0-I are more likely to belong to GLM in mass stage.There are some differences in ultrasound blood flow signals under different TCM syndrome types of GLM in mass stage.Ultrasound blood flow signal can be used to assist the diag-nosis of TCM syndrome differentiation of GLM in mass stage.
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