Objective To investigate the effect of bone cement dispersion distribution on the clinical efficacy and pain relief of percutaneous vertebroplasty(PVP)for the treatment of osteoporotic spinal fractures.Methods A retrospective analysis was conducted on 100 patients with osteoporotic vertebral compression fractures(OVCF)who underwent PVP treatment at the affili-ated xiangdong Hospital of Hunan Normal University from January 2021 to January 2023.The degree of bone cement disper-sion was evaluated based on postoperative X-ray films,and the patients were divided into a well dispersed group(n=57)and a poorly dispersed group(n=43).Comparing the general information,VAS score,anterior vertebral height ratio,and postoperative recovery rate of mid column height between two groups of patients.Results The VAS scores of the two groups on the 3rd day after the operation,the 3rd month after the operation and the 6th month after the operation were lower than the preoperative pe-riod.There was no statistical difference in the VAS score of the two groups at the same time before and after the operation;the anterior edge height ratio of the vertebral edge of the patients in the good dispersion group was significantly higher than that of the poor dispersion group,the degree of the vertebral collapse of the patients in the well dispersed group was significantly lower than that of the poorly dispersed group,and the postoperative middle column height recovery rate of the patients in the well dis-persed group was significantly higher than that of the poorly dispersed group.Conclusion PVP surgery for OVCF can effectively alleviate pain,and the better the dispersion of bone cement,the more significant the supportive effect it plays.