首页|Effects of post-dilation on coronary blood flow and MACE events following primary percutaneous coronary intervention in patients with STEMI
Effects of post-dilation on coronary blood flow and MACE events following primary percutaneous coronary intervention in patients with STEMI
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Objective: This retrospective cohort study aimed to evaluate the effect of post-dilation on coronary blood flow and MACE events during hospitalization and 1 year follow-up following primary PCI in patients with ST-segment. Methods: 419 eligible patients who underwent PPCI due to STEMI between January 2015 and October 2019 were enrolled. The CTFC, final QCA, and the incidence of no-reflow/slow-flow during different procedure moments were assayed. Study end points was to compare two groups of patients with clinical characteristics, compared two groups of patients with the incidence of no-reflow and slow-flow, and the incidence of MACE during hospitalization and 1-year follow-up. Results: The incidence of final no-reflow/slow-flow in the post-dilation group was not significantly higher than that in the non-post-dilation group (24.3％ vs.19.4％; p = 0.238).There was no significant statistical difference in MACE events during hospitalization, but for the 1-year follow-up, the incidence of Target vessel revascularization and Target lesion revascularization in the post-dilation group was lower than that in the non-post-dilation group. A multivariable logistic regression model revealed that age (OR=1.078, 95％CI=1.038-1.120; P <0.001), history of diabetes (OR=3.009, 95％CI=1.183-7.654; P =0.021), post-dilation (OR=0.192, 95％CI=0.067-0.549; P=0.002) were independently correlated with long-term follow-up of MACE.Conclusion: Post-dilation does not increase poor prognosis during hospitalization, and reduces the incidence of TVR and TLR events during long-term follow-up.
Post-dilationPrimary PCISTEMINo-reflowSlow-flow
Meng-Cheng Xu、Hua-Su Zeng、Li Fan、Yang Zhuo、Jun Gu、Jun-Feng Zhang、Yu-Qi Fan、Chang-Qian Wang
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Department of Cardiology,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China
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维普
