首页|Screening microRNA expression profile in patients with acute T cell mediated rejection after kidney transplantation
Screening microRNA expression profile in patients with acute T cell mediated rejection after kidney transplantation
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原文链接
NETL
NSTL
万方数据
维普
Objective: To explore the expression profile of miRNA in peripheral blood of patients with acute T cell mediated rejection after kidney transplantation. Method: 4 patients with acute T cell mediated rejection(TCMR) after kidney transplantation were collected as experimental group. Meanwhile,4 patients under stable condition after kidney transplantation were collected as control group. The elbow blood was taken from two groups. The next generation sequencing was used to study miRNA libraries. Then, they were analyzed of variance by R language software. Results: 14 miRNAs were differently expressed in the experimental group and control group, including 5 up-regulated miRNAs (P<0.05) and 9 down-regulated miRNAs (P<0.05). Conclusions: Peripheral blood miRNAs expression variations might be ideal biomarkers and reveal mechanisms for acute TCMR.
Kidney transplantationAcute T cell mediated rejection miRNA
NETL
NSTL
万方数据
维普
