首页|Research progress and comparison of the establishment of animal models of radiotherapy or chemotherapy-induced oral mucositis

Research progress and comparison of the establishment of animal models of radiotherapy or chemotherapy-induced oral mucositis

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The mechanism of radiotherapy or chemotherapy-induced oral mucositis is not yet clear.And model establishment is needed in further study.In order to summarize the methods of model establishment and make a comparison,literature databases including Web of Science、Pubmed and CNKI were searched for related researches from January 2015 to January 2021. Hamsters, mice, rats,guinea pigs and miniature pigs were chosen to be modeling animals and modeling methods could be classified into: chemotherapy, chemotherapy combined with superficial mucosal irritation, radiotherapy, radiotherapy combined with superficial mucosal irritation and chemoradiotherapy. Advantages and disadvantages had been analyzed in this study to provide reference for following studies.

RadiotherapyChemotherapyOral mucositisAnimal modelResearch progress

Chen Chen、Ran Yu、Dong-Mei Chen、Chao Deng、Yan-Ni Lou、Li-Qun Jia

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Clinical Medical College of China-Japan Friendship Hospital,Beijing University of Chinese Medicine,Beijing 100029,China

China-Japan Friendship Hospital,Beijing 100029,China

国家自然科学基金

81973693

2022

海南医科大学学报(英文版)

海南医科大学学报(英文版)

ISSN:
年,卷(期):2022.28(15)
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