首页|Efficacy and prognosis of vacuum‑assisted excision for benign intraductal papilloma of breast: A meta‑analysis
Efficacy and prognosis of vacuum‑assisted excision for benign intraductal papilloma of breast: A meta‑analysis
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Objective: To evaluate the safety and effectiveness of vacuum‑assisted excision for benign intraductal papilloma of breast. Methods: The databases including PubMed, Embase, Cochrane Library, WangFang, CNIK, VIP and Web of Science were searched by computer, according the inclusion and exclusion criteria after screening of literature. The Cochrane handbook and Newcastle‑Ottawa scale was used to evaluate the studies. Then the Review Manager 5.3 software was to used analyze the data.Results: A total of 1016 patients was included in 9 articles. The amount of blood loss in vacuum‑assisted surgery was less than that in open surgery [MD=-6.38,95％CI(-9.90,-2.86),P<0.05]. The drainage[MD=-2.56,95％CI(-4.97,-0.15 ,P<0.05] and drainage time[MD=-0.25,95％CI(-0.40,-0.09),P<0.05] in vacuum‑assisted surgery was less than that in open surgery. There were also few postoperative complications than that in open surgery [ RR=0.43,95％CI(0.29,0.64),P<0.05]. Compared with open surgery, the postoperative recurrence rate was lower in vacuum‑assisted surgery [RR=0.26,95％CI (0.14, 0.49), P<0.05]. Last,there was no statistically significant difference in the operative time between vacuum‑assisted surgery and open surgery,[SD=-12.82,95％CI (-25.70, 0.06),P=0.05].Conclusion: Compared with open surgery, vacuum‑assisted excision has the advantages of less blood loss and lower postoperative complications, but the operative time is not statistically significant compared with open surgery. In addition, compared with open surgery in this study, vacuum‑assisted excision has the advantages of lower recurrence rate, but it still needs long‑term dynamic observation.
Intraductal papilloma of breastVacuum‑assisted excisionMeta analysisEffectPrognosis
SU Ya?jing、WU Huan?liang、CHEN Yun?jing、HE Gui?sheng、WU Huang?fu
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Hainan Medical University,Haikou 570100,China
Hainan Cancer Hospital,Haikou 570100,China
The Second Affiliated Hospital of Hainan Medical University,Haikou 570100,China
海南省重点研发计划In-Hospital Project of the Second Affiliated Hospital of Hainan Medical UniversitySecond Affiliated Hospital of Haiyi Medical University
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