首页|Study on TCM intervention of NF-κB signal pathway in the treatment of bronchial asthma

Study on TCM intervention of NF-κB signal pathway in the treatment of bronchial asthma

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Bronchial asthma (asthma for short) is a common chronic respiratory disease inchildren, which has adverse effects on children's physical and mental health. Nuclear factor κB (NF-κB) signaling pathway is an important transcription factor in airway inflammation, and plays an important role in airway inflammation and airway remodeling in asthma. Clinical studies have found that traditional Chinese medicine has positive effects in the treatment of asthma. Hence, this paper aims to review the literatures on the treatment of asthma through traditional Chinese medicine compound and single herbs and extracts by regulating the NF-κB signaling pathway for nearly a decade. It is found that traditional Chinese medicine can inhibit airway inflammation, relieve airway smooth muscle spasm and reduce airway resistance through the regulation of NF-κB signaling pathway, so as to play a key role in the treatment of asthma, and provide a scientific basis for the treatment of asthma with traditional Chinese medicine.

Bronchial asthmaNF-κBTraditional Chinese medicineResearch overview

LAI Hai-yan、YI Wei、DENG Kun、LONG Juan、REN Meng-yao、QIAO Yun、ZHOU Bei、LI Wei-wei

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The First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530299,China

College of Acupuncture-Moxibustion and Tuina,Guangxi University of Chinese Medicine,Nanning 530299,China

College of Pharmacy,Guangxi University of Chinese Medicine,Nanning 530299,China

Graduate School of Guangxi University of Chinese Medicine,Nanning 530000,China

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国家自然科学基金广西科技厅重点研发计划Universitylevel Postgraduate Research Innovation Project of Guangxi University of Chinese Medicine(2021)

81860867Guike AB18221030YCXJ2021037

2022

海南医科大学学报(英文版)

海南医科大学学报(英文版)

ISSN:
年,卷(期):2022.28(21)
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