Predictive Value of Systemic Immune-inflammatory Index for No-reflow after PCI in Patients with Acute ST Segment Elevation Myocardial Infarction
[Objective]To investigate the predictive value of systemic immune-inflammatory index(SII)for no-reflow after percutaneous coronary intervention(PCI)in patients with acute ST segment elevation myocardial in-farction(STEMI).[Methods]The clinical data of 208 STEMI patients who underwent PCI in our hospital from January 2016 to April 2020 were retrospectively analyzed.According to whether no-reflow occurred after PCI,they were divided into normal reflow group and no-reflow group.The general clinical data of the two groups were com-pared.Cox multivariate regression analysis was used to analyze the risk factors of no-reflow.Receiver operating characteristic(ROC)curve was used to evaluate the predictive value of reperfusion time,HbA1c and SII for no-re-flow.According to the cut-off value of SII to predict no-reflow,the patients were divided into SII low-level group and SII high-level group.The 3-year survival rates between normal reflow group and no-reflow group,SII low-lev-el group and SII high-level group were compared.[Results]The proportion of patients with TIMI grade＞2 and the proportion of diabetes mellitus in the no-reflow group were higher than those in the normal reflow group,and the levels of STB,DTB,CK-MB peak,HDL,postprandial blood glucose,FPG and SII in the no-reflow group were higher than those in the normal reflow group,with statistically significant differences(P＜0.05).Cox multi-variate regression analysis showed that STB,DTB,HbA1c and SII were the relevant factors affecting no-reflow(P＜0.05).ROC curve analysis showed that STB,DTB,HbA1c and SII had predictive value for no-reflow,but SII had higher predictive value for no-reflow than STB,DTB and HbA1c(Z= 3.965,4.201,4.062;P =0.018,0.014,0.021).The 3-year survival rate in the no-reflow group was 56.3%(27/48),which was lower than 80.6%(129/160)in the normal reflow group,and the difference was statistically significant(P＜0.05).The 3-year sur-vival rate in the SII high-level group was 30.8%(20/65),which was lower than 84.2%(80/95)in the SII low-level group,and the difference was statistically significant(P＜0.05).[Conclusion]SII can predict the occurrence of no-reflow after PCI in patients with STEMI,and can affect the postoperative survival rate of patients.
ST Elevation Myocardial Infarction/SUAcute DiseasePercutaneous Coronary Intervention
万方数据
维普
