Evaluation Value of FT3 and FT4 Levels in Patients with Hyperthyroidism Complicated with Hy-perthyroid Heart Disease
[Objective]To explore the evaluation value of serum free triiodothyronine(FT3)and free thy-roxine(FT4)in patients with hyperthyroidism complicated with hyperthyroid heart disease.[Methods]A total of 84 patients with hyperthyroidism treated in Chang'an District Hospital from January 2021 to January 2023 were selected in the study.The incidence of hyperthyroidism patients complicated with hyperthyroidism heart disease was counted,and patients were divided into concurrent group(10 cases)and non-concurrent group(74 cases)according to whether hyperthyroidism heart disease occurred.The clinical data of patients in concurrent group and non-concurrent group were compared.Multivariate logistic regression analysis was used to analyze the risk factors of hyperthyroidism patients complicated with hyperthyroidism heart disease.The efficacy of FT3 and FT4 in the evaluation of hyperthyroidism patients complicated with hyperthyroidism heart disease was analyzed.[Results]There were 10 cases of hyperthyroid patients complicated with hyperthyroid heart disease,which showed that the incidence of hyperthyroid heart disease was 11.90%.There were no significant differ-ences in gender,age,diabetes mellitus,smoking history,hyperthyroidism drug use,uric acid,triglyceride,hemoglobin,albumin and infection between the concurrent group and the non-concurrent group(P＞0.05).FT3 and FT4 in the concurrent group were higher than those in the non-concurrent group(P＜0.05).The re-sults of multivariate analysis showed that both FT3 and FT4 were independent risk factors for hyperthyroid pa-tients complicated with hyperthyroid heart disease(OR =3.256,3.368,P＜0.05).The best cutoff points of FT3 and FT4 in predicting hyperthyroidism complicated with hyperthyroidism heart disease were 10.25 pmol/L and 36.52 pmol/L respectively,and the area under the curve(AUC)was 0.785 and 0.756.The specificity of the combination of FT3 and FT4 was 92.69%,which was higher than that of FT3 and FT4 alone(P＜0.05).[Conclusion]The incidence of hyperthyroid patients complicated with hyperthyroid heart disease is high.FT3 and FT4 have certain value in the evaluation of hyperthyroid patients complicated with hyperthyroid heart dis-ease,but the value of their combined detection is even higher,which can be used as an important reference in-dex for clinical evaluation.
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