首页|孕妇下生殖道感染状态下微生物紊乱情况及对妊娠结局的影响

孕妇下生殖道感染状态下微生物紊乱情况及对妊娠结局的影响

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[目的]探讨孕妇下生殖道感染状态下微生物紊乱情况及对妊娠结局的影响.[方法]选取 2019 年 1 月至 2022 年 1 月在西安高新医院就诊的 96 例孕妇,根据生殖道病原微生物培养结果将患者分为观察组(结果阳性,n =44)和对照组(结果阴性,n =52),比较两组孕妇白细胞计数、中性粒细胞、C 反应蛋白水平、不良妊娠结局及新生儿不良并发症总发生率.[结果]96 例孕妇中下生殖道感染 44 例(45.83%),感染病原体包括细菌、真菌、衣原体、支原体、解脲脲原体、滴虫.细菌感染率为 38.64%,真菌感染率为 13.64%,衣原体感染率为 15.91%,支原体感染率为 18.18%,解脲脲原体感染率为 2.27%,滴虫感染率为 11.36%.观察组孕妇白细胞计数、中性粒细胞、C反应蛋白显著高于对照组,差异有统计学意义(P<0.05);观察组孕妇胎膜早破、宫内感染、产褥期感染等不良妊娠结局总发生率为 22.73%,显著高于对照组的 3.85%,差异有统计学意义(P<0.05);观察组新生儿败血症、病理性黄疸、新生儿肺炎等不良并发症总发生率为 25.00%,显著高于对照组的 3.85%,差异有统计学意义(P<0.05).[结论]孕妇下生殖道感染病原体主要包括细菌、真菌、衣原体、支原体、解脲脲原体、滴虫,孕妇下生殖道感染会增加不良妊娠结局、新生儿不良并发症总发生率,发现感染后应及时进行治疗.
Microbiological Disorder in Pregnant Women with Lower Reproductive Tract Infection and its In-fluence on Pregnancy Outcome
[Objective]To investigate microbiological disorder in pregnant women with lower reproductive tract infection and its impact on pregnancy outcomes.[Methods]A total of 96 pregnant women in Xi'an Gaoxin Hospital from January 2019 to January 2022 were selected as research subjects,and patients were divided into the observa-tion group and the control group according to the culture results of reproductive tract pathogens.There were 44 pa-tients with pathogen positive culture in the observation group,and 52 cases with pathogen negative culture in the control group.The measurement of white blood cells,neutrophils and C-reactive protein,the occurrence of adverse pregnancy outcomes,and the total incidence of adverse neonatal complications were compared between the two groups.[Results]Among the 96 pregnant women,there were 44 cases of lower genital tract infection showing the infection rate was 45.83%.Infectious pathogens included bacteria,fungi,chlamydia,mycoplasma,uplasma urea-lyticum,and trichomonas,The bacterial infection rate was 38.64%,the fungal infection rate was 13.64%,the chlamydia infection rate was 15.91%,the mycoplasma infection rate was 18.18%,the infection rate of urealyticum was 2.27%,and the trichomonas infection rate was 11.36%.Maternal leukocytes,neutrophils,and C-reactive protein in the observation group were significantly higher than those in the control group with statistically signifi-cant difference(P<0.05).The overall incidence of adverse pregnancy outcomes such as premature rupture of membranes,intrauterine infection and puerperium infection in the observation group was 22.73%,which was high-er than the 3.85%in the control group with the statistically significant difference(P<0.05).The overall incidence of adverse complications such as neonatal sepsis,pathological jaundice,and neonatal pneumonia was 25.00%in the observation group,which was higher than that of 3.85%in the observation group.The difference was statistically significant(P<0.05).[Conclusion]The pathogens of lower reproductive tract infection in pregnant women mainly include bacteria,fungi,chlamydia,mycoplasma,urealyplasma urealyticum and trichomonas.Lower reproductive tract infection in pregnant women will increase the total incidence of adverse pregnancy outcomes and adverse neo-natal complications.Thus,infections should be treated timely and promptly once the infection are discovered.

Reproductive Tract Infections/MIPregnancy Outcome

张金辉、张溪

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西安高新医院产科VIP,陕西 西安 710077

西安市鄠邑区中医医院检验科,陕西 西安 710300

生殖道感染/微生物学 妊娠结局

2024

医学临床研究
湖南省医学会

医学临床研究

影响因子:0.595
ISSN:1671-7171
年,卷(期):2024.41(3)
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