Comparison of Clinical Efficacy between Pipeline Embolization Device and Stent Assisted Coil Embolization in the Treatment of Large Cerebral Aneurysms
[Objective]To explore the clinical efficacy of Pipeline embolization device(PED)and stent as-sisted coil placement(SAC)in the treatment of large cerebral aneurysms.[Methods]A retrospective analysis was conducted on the clinical data of 82 patients with intracranial aneurysms with a diameter of≥10 mm ad-mitted to our hospital from December 2017 to December 2021.Among them,43 patients received PED treat-ment(PED group)and 39 patients received SAC treatment(SAC group).We compared the surgical results of two groups of patients,and compared the results of immediate digital subtraction angiography(DSA)and modified Rankin Scale(mRS)scores at admission and discharge between the two groups.Two groups of pa-tients were followed up 12 months after surgery,and the mortality,recurrence,DSA examination results,and mRS score distribution were compared between the two groups at 6 and 12 months after discharge.[Results]In this study,82 patients successfully completed surgery,including 45 PEDs implanted in the PED group,16 pure PEDs implanted,25 PEDs combined with spring coil filling,and 2 double PEDs implanted.There was no statistically significant difference in the dense embolism rate between the two groups of immediate postopera-tive DSA examination results(P＞0.05).There was no statistically significant difference in the distribution of mRS scores between the two groups at admission and discharge(P＞0.05).There was no statistically signifi-cant difference in the incidence and mortality of perioperative complications between the two groups(P＞0.05).At the 6-12 month follow-up after discharge,the dense embolism rate in the PED group was higher than that in the SAC group,and the differences were statistically significant(all P＜0.05).The proportion of mRS scores≤2 in the PED group for follow-up at 6 and 12 months after discharge was higher than that in the SAC group,and the differences were statistically significant(all P＜0.05).[Conclusion]The clinical efficacy and short-term prognosis of PED treatment for large intracranial aneurysms are comparable to those of SAC,but PED shows certain advantages in improving long-term prognosis.
万方数据
维普
