Mycoplasma Culture Results and Antimicrobial Resistance Analysis in Patients with Urinary and Genital Tract Infections
[Objective]To understand and analyze the mycoplasma culture results and antimicrobial resistance of pa-tients with urinary and genital tract infections in our hospital.[Methods]The secretions from the urinary and genital tracts of 188 patients who were treated in our hospital were tested the mycoplasma infection and analyze the related drug sensi-tivity.[Results]Among 188 mycoplasma culture specimens,the positive rate was 44.68％(84/188),with 16 males and 68 females.Of these,63 cases(33.51％)were solely infected with Ureaplasma urealyticum(Uu),6 cases(3.19％)were sole-ly infected with Mycoplasma hominis(Mh),and 15 cases(7.98％)had co-infection with Uu and Mh.The rate of Uu in-fection alone was higher in females than in males(P＜0.05).No significant difference was found in the rate of infection with Mh alone or co-infection with Uu and Mh between males and females(P＞0.05).Among the 84 positive cases,the highest proportion was in the age of 20-30 group(34.12％),followed by the age of 31-40 group(16.87％),with fewer cases in the age＜20 group(7.62％)and＞50 group(8.52％).There was no significant difference in the positive rate of infection across age groups between males and females(P＞0.05).Among the 63 cases solely infected with Uu,higher antibiotic sensitivity was observed for minocycline,doxycycline,clarithromycin,and josamycin,with the highest resist-ance to sparfloxacin,followed by clindamycin.For the 6 cases solely infected with Mh,higher sensitivity was found to josamycin and minocycline,with the highest resistance to roxithromycin,clarithromycin,azithromycin,and erythromy-cin.For the 15 cases of co-infection with Uu and Mh,higher sensitivity was found to minocycline,doxycycline,with the highest resistance to roxithromycin,erythromycin,and azithromycin.[Conclusion]Mycoplasma infection in our hospital is predominantly by Uu,most commonly seen in women aged 20-30,which is antibiotic sensitive to minocycline,doxycyc-line,and josamycin.
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