Influence of Calcified Plaque Characteristics on the Diagnostic Results of Vascular Stenosis in CT Coronary Angiography
[Objective]To investigate the influence of calcified plaque characteristics on the diagnostic results of vas-cular stenosis in CT coronary angiography.[Methods]A total of 102 coronary heart disease patients with calcified plaques treated in our hospital were selected as the observation group,and 80 coronary heart disease patients without calcified plaques treated during the same period were selected as the control group.All patients underwent CT coronary angiogra-phy and digital subtraction angiography(DSA)to examine the characteristics of calcified plaques.To analyze the impact of different degrees of plaque calcification on the diagnosis of vascular stenosis by CT coronary angiography.[Results]In the observation group of 102 patients with calcified plaques,189 sites of stenosis were identified,including 54 sites caused by non-calcified plaques,78 sites by mildly to moderately calcified plaques,and 57 sites by severely calcified plaques.The di-agnostic consistency between CT coronary angiography and DSA was high for non-calcified plaques(Kappa=0.904,P＜0.05),relatively high for mildly to moderately calcified plaques(Kappa=0.822,P＜0.05),and moderate for severely calcified plaques(Kappa=0.541,P＜0.05).In the control group of 80 patients,DSA diagnosed 98 sites of stenosis,in-cluding 53 sites of mild stenosis and 45 sites of significant stenosis.The diagnostic consistency between CT coronary angi-ography and DSA was high(Kappa=0.979,P＜0.05).The sensitivity comparison between mildly to moderately calci-fied plaques and severely calcified plaques showed no statistical significance(P＞0.05);however,there were statistically significant differences in the specificity and accuracy between the two groups(P＜0.05).[Conclusion]In the presence of calcified plaques,CT coronary angiography demonstrates high sensitivity but low specificity in diagnosing vascular steno-sis.And the presence of severe calcified plaques has more significantly impact on the specificity.
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