首页|手术与保守治疗在高龄恶性肿瘤相关性急性肠梗阻中的应用效果及预后影响因素分析

手术与保守治疗在高龄恶性肿瘤相关性急性肠梗阻中的应用效果及预后影响因素分析

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[目的]探讨手术与保守治疗在高龄恶性肿瘤相关性急性肠梗阻中的应用效果及预后影响因素分析.[方法]对本院收治的96例高龄急性肠梗阻患者的临床资料进行回顾性分析,其中71例根据病情予以肠切除肠吻合术、肠造口或肠外置术治疗,25例予以胃肠减压等保守治疗,根据治疗2个月后的预后结局分为预后良好组(79例)和预后不佳组(17例),分析患者预后的影响因素.[结果]71例手术组患者治疗成功率为94.37%(67/71),高于25例非手术组患者的48.00%(12/25)(P<0.05).两组患者术后并发症总发生率比较,差异无统计学意义(P>0.05).预后不佳组病理分期Ⅲ期、肿瘤低分化占比及年龄均高于预后良好组(P<0.05).Logistic多因素回归分析结果显示,年龄、病理分期、肿瘤分化程度均为患者预后的影响因素(P<0.05).[结论]相对于非手术方案,高龄恶性肿瘤相关性急性肠梗阻患者应用手术治疗更有助于缓解肠梗阻症状,而患者年龄、病理分期和肿瘤分化程度均可对预后产生影响.
Analysis of the Application Effects and Prognostic Factors of Surgery and Conservative Treat-ment in Elderly Patients with Malignant Tumor-Related Acute Intestinal Obstruction
[Objective]To investigate the effects of surgery and conservative treatment in elderly patients with malignant tumor-related acute intestinal obstruction and to analyze the factors influencing prognosis.[Methods]A retrospective analysis was conducted on the medical records of 96 elderly patients with acute in-testinal obstruction admitted to our hospital.Among them,71 patients were treated with bowel resection and anastomosis,stoma creation,or bowel exteriorization based on their condition,while 25 patients received con-servative treatment such as gastrointestinal decompression.The patients were divided into a good prognosis group(79 cases)and a poor prognosis group(17 cases)based on the prognosis two months after treatment.The factors influencing prognosis were analyzed.[Results]The treatment success rate was 94.37%(67/71)in the surgery group,which was higher than the 48.00%(12/25)in the non-surgery group(P<0.05).There was no statistically significant difference in the overall incidence of postoperative complications between the two groups(P>0.05).The poor prognosis group had higher proportions of pathological stage Ⅲ,low differ-entiation of tumors,and older age compared to the good prognosis group(P<0.05).Logistic multivariate re-gression analysis showed that age,pathological stage,and tumor differentiation degree were factors influen-cing prognosis(P<0.05).[Conclusion]Compared to non-surgical treatment,surgical treatment is more ef-fective in alleviating symptoms of intestinal obstruction in elderly patients with malignant tumor-related acute intestinal obstruction.Factors such as patient age,pathological stage,and tumor differentiation degree can in-fluence prognosis.

Neoplasms/COIntestinal Obstruction/CONeoplasms/SUIntestinal Obstruction

王红芳、李培满、耿鹏

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漯河市中医院外科,河南 漯河 462000

肿瘤/并发症 肠梗阻/并发症 肿瘤/外科学 肠梗阻

2024

医学临床研究
湖南省医学会

医学临床研究

影响因子:0.595
ISSN:1671-7171
年,卷(期):2024.41(7)
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