The Role of FVH/DWI Mismatch in Predicting the Recanalization Rate after Mechanical Throm-bectomy in Acute Anterior Circulation Large Vessel Occlusion
[Objective]To investigate the relationship of fluid-attenuated inversion recovery vascular hyperintensity(FVH)/diffusion-weighted imaging(DWI)mismatch with the recanalization rate after mechanical thrombectomy in pa-tients with acute anterior circulation large vessel occlusion(LVO).[Methods]A total of 127 patients with acute anterior circulation LVO underwent MRI and mechanical thrombectomy,and their post-procedural recanalization rates were evalu-ated.[Results]Of the 127 patients,98 achieved complete recanalization(Group A),while 29 had no or partial recanaliza-tion(Group B),with an overall recanalization rate of 77.17%.No statistically significant differences were observed be-tween Group A and Group B regarding gender,age,comorbidities,occlusion site,time from onset to MRI,or NIHSS scores on admission(P>0.05).Group A had a higher proportion of good collateral circulation and lower 3-month modi-fied Rankin Scale(mRS)scores compared to Group B(P<0.05).Group A also had higher FVH scores,a greater pro-portion of FVH/DWI mismatch,and smaller DWI infarct volumes compared to Group B(P<0.05).Spearman correla-tion analysis showed a positive correlation between FVH/DWI mismatch and recanalization rate after mechanical throm-bectomy in acute anterior circulation LVO(rs=0.415,P=0.005).Logistic regression analysis identified collateral cir-culation,3-month mRS score,and FVH/DWI mismatch as factors associated with recanalization(P<0.05).[Conclu-sion]Patients with FVH/DWI mismatch have a higher recanalization rate after mechanical thrombectomy for acute anteri-or circulation large vessel occlusion,which warrants clinical attention.