Surgical Treatment and Rehabilitation of Femoral Shaft Fractures or Deformities in Children with Osteogenesis Imperfecta
Objective To explore and evaluate the clinical effect of surgical treatment and rehabilitation of osteogenesis imperfecta in children.Methods The data of 31 children with osteogenesis imperfecta which were treated in the Orthopedics Department of the Second Affiliated Hospital of Zhengzhou University from June 2014 to June 2020 were analyzed,with a total of 51 femurs,including 18 males and 13 females,aged from 3 years and 3 months to 14 years and 6 months,with an average age of(124.41±33.13)months.All patients were accepted surgies of FD-extended intramedullary nailing,postoperative rehabilitation exercises,oral calcium and vitamin D preparations,adjuvant bisphosphonates were used,followed up regularly,and the efficacy was evaluated according to Barthel score and functional independence measure(WeeFIM)before and 1.5 years after surgery.Results All 31 children were followed up.Except for 1 patient who accepted a surgery of FD-extended intramedullary nailing for the second time,no refracture occurred.The Barthel score increased from(52.10±5.88)points before operation to(85.16±7.13)points after operation.The WeeFIM score increased from(58.00±13.80)points before operation to(83.14±8.16)points,and the difference was statistically significant(P<0.05).Conclusion FD-extended intramedullary nailing combined with postoperative anti-osteoporosis medication and regular rehabilitation exercise can significantly improve patients'daily activities and quality of life.