Distribution of Pathogenic Bacteria and Influencing Factor of Drug-Resistant Bacteria Infection in Patients with Colorectal Cancer After Operation
Objective To investigate the distribution of drug-resistant bacteria and the influencing factors of infection in patients with colorectal cancer after surgery.Methods A total of 170 patients with colorectal cancer after surgery in Henan Provincial Hospital of Traditional Chinese Medicine from October 2021 to July 2023 were selected and divided into infected group(36 cases)and non-infected group(134 cases)according to whether incision infection occurred after surgery.The incision secretions of patients in the infected group were collected for pathogen culture,the distribution of pathogenic bacteria was analyzed,and the general data of the two groups were compared.The factors causing infection were analyzed by logistic regression model.Results The incidence of Ⅲ+Ⅳ stage,operation time＞3 hours,body mass index(BMI)≥ 24 kg·m-2,diabetes mellitus in infected group was higher than that in uninfected group(P＜0.05).BMI ≥24 kg·m-2,Ⅲ+Ⅳ stage,diabetes mellitus,and operation time＞3 hours were independent risk factors for postoperative incision infection(P＜0.05).Gram-negative bacteria and Gram-positive bacteria were 78.57％and 21.43％in postoperative incision infection samples.Conclusion The risk factors for postoperative incision infection in patients with colorectal cancer are stage Ⅲ+Ⅳ,diabetes mellitus,BMI≥24 kg·m-2,and operation time＞3 hours.Early prevention and treatment measures can be targeted to reduce the risk of incision infection.Moreover,the distribution of pathogenic bacteria in incision infection is diverse,so clinical treatment plans should be formulated according to the results of pathogen culture.
万方数据
维普
