首页|退行性腰椎管狭窄患者椎间孔镜术后下腰痛的危险因素及风险预测模型构建

退行性腰椎管狭窄患者椎间孔镜术后下腰痛的危险因素及风险预测模型构建

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目的 分析退行性腰椎管狭窄(DLSS)患者椎间孔镜术后下腰痛的危险因素及风险预测模型构建.方法 本研究采用前瞻性分析,纳入2020年7月至2022年7月南阳市中心医院收治的86例行经皮椎间孔镜手术治疗的DLSS患者为研究对象,术后随访3个月,根据术后下腰痛发生情况,分为发生组和未发生组,分析两组患者临床资料,采用多因素logistic回归分析DLSS患者椎间孔镜术后下腰痛发生的影响因素,构建风险预测模型,绘制受试者工作特征(ROC)曲线评估风险模型的预测效能.结果 随访3个月,86例DLSS患者行椎间孔镜术后发生下腰痛患者21例,发生率为24.42%(21/86);发生组骨质疏松、术中清理椎间隙、术后椎管内无菌性炎症、首次锻炼时间与未发生组比较,差异无统计学意义(P<0.05);经多因素logistic回归分析,结果显示,骨质疏松、术中清理椎间隙、术后椎管内无菌性炎症、首次接受锻炼时间均是DLSS患者椎间孔镜术后下腰痛发生的危险因素(P<0.05);构建风险模型,验证模型显示C-index值为0.870,具有良好区分度,绘制标准曲线显示,校准曲线和Y-X直线相近,模型准确度良好;对模型预测效能进行验证,结果显示,风险模型评估DLSS患者椎间孔镜术后下腰痛发生的曲线下面积(AUC)为0.870,95%CI为0.779~0.961,P<0.001.结论 DLSS患者行椎间孔镜术后下腰痛发生率较高,合并骨质疏松、术中未清理椎间隙、有术后椎管内无菌性炎症、首次接受锻炼时间延长均是DLSS患者行椎间孔镜术后发生下腰痛的危险因素,基于以上因素构建的风险模型对DLSS患者行椎间孔镜术后是否发生下腰痛具有较高的评估价值.
Risk Factors and Risk Prediction Model Construction of Low Back Pain After Intervertebral Foramen Endoscopy in Patients with Degenerative Lumbar Spinal Stenosis
Objective To analyze the risk factors of low back pain in patients with degenerative lumbar spinal stenosis(DLSS)after intervertebral foramen endoscopic surgery and to establish a risk prediction model.Methods A prospective analysis was used in this study,and 86 patients with DLSS who were treated by percutaneous intervertebral foramen surgery in Nanyang Central Hospital from July 2020 to July 2022 were included in the study.They were followed up for 3 months after surgery.According to the occurrence of postoperative low back pain,they were divided into the occurrence group and the non occurrence group.The clinical data of the two groups of patients were analyzed,and the influencing factors of the occurrence of low back pain in DLSS patients after intervertebral foramen endoscopy were analyzed by multifactorial logistic regression.The risk prediction model was constructed,and the receiver operating characteristic(ROC)curve was drawn to evaluate the prediction efficiency of the risk model.Results Following up for 3 months,21 of 86 patients with DLSS developed low back pain after intervertebral foramen endoscopy,the incidence rate was 24.42%(21/86).There were statistical significant differences in the occurrence group of osteoporosis,intraoperative clearance of intervertebral spaces,postoperative aseptic inflammation in the spinal canal(P<0.05).Multivariate logistic regression analysis showed that osteoporosis,clearance of intervertebral space during operation,aseptic inflammation in vertebral canal after operation,and the time of first exercise were all risk factors for low back pain after intervertebral foramen endoscopy in DLSS patients(P<0.05).The risk model was constructed,and the verification model showed that the C-index value was 0.870,which had good discrimination.The standard curve was drawn,and the calibration curve was similar to the Y-X straight line,and the model accuracy was good.The predictive efficacy of the model was verified.The results showed that the area under the curve(AUC)of the risk model for evaluating the occurrence of low back pain in DLSS patients after intervertebral foramen was 0.870,and the 95%CI was 0.779-0.961,P<0.001.Conclusion The incidence of low back pain in DLSS patients after intervertebral foramen endoscopic surgery is high.The risk factors of low back pain in DLSS patients after intervertebral foramen endoscopic surgery are osteoporosis,uncleaned intervertebral space during surgery,aseptic inflammation in the spinal canal after surgery,and prolonged first exercise time.The risk model based on the above factors has a high evaluation value for whether there is low back pain in DLSS patients after intervertebral foramen endoscopic surgery.

degenerative lumbar spinal stenosisintervertebral foramen endoscopypostoperative lower back painrisk factorrisk model

梁雁冰、王云阁、艾彬彬

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南阳市中心医院骨三科,河南南阳 473000

退行性腰椎管狭窄 椎间孔镜术 术后下腰痛 危险因素 风险模型

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(1)
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