首页|健脾逐瘀方联合中药穴位敷熨治疗老年特发性膜性肾病脾虚肾瘀证的效果

健脾逐瘀方联合中药穴位敷熨治疗老年特发性膜性肾病脾虚肾瘀证的效果

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目的 探讨健脾逐瘀方联合中药穴位敷熨治疗老年特发性膜性肾病脾虚肾瘀证的临床效果.方法 本研究为前瞻性随机对照研究,依据随机数字表法将2021年2月至2022年6月新密市中医院收治的100例老年特发性膜性肾病脾虚肾瘀证患者分为对照组(50例,常规基础治疗+中药穴位敷熨)和观察组(50例,常规基础治疗+中药穴位敷熨+健脾逐瘀方治疗),均持续治疗3个月.比较治疗3个月时临床疗效,以及治疗前和治疗3个月时肾功能指标、血液流变学水平;并统计治疗期间不良反应发生情况.结果 对照组治疗总有效率低于观察组(P<0.05);治疗3个月后,对照组血尿素氮、24 h尿蛋白定量、血肌酐高于观察组(P<0.05);治疗3个月后,对照组纤维蛋白原、D-二聚体、血浆黏度水平高于观察组(P<0.05);两组治疗期间不良反应率比较,差异无统计学意义(P>0.05).结论 健脾逐瘀方联合中药穴位敷熨治疗老年特发性膜性肾病脾虚肾瘀证的临床效果显著,有助于缓解患者症状,改善肾功能水平和血液流变学指标,且未明显增加不良反应.
Therapeutic Effect of Jianpi Zhuyu Formula Combined with Traditional Chinese Medicine Acupoint Application and Ironing on Elderly Idiopathic Membranous Nephropathy with Spleen Deficiency and Kidney Stasis Syndrome
Objective To explore the clinical effect of Jianpi Zhuyu Formula combined with traditional Chinese medicine acupoint application and ironing in the treatment of elderly idiopathic membranous nephropathy with spleen deficiency and kidney stasis syndrome.Methods This study was a prospective randomized controlled study.According to the random number table method,100 elderly patients with idiopathic membranous nephropathy with spleen deficiency and kidney stasis syndrome admitted to Xinmi Hospital of Traditional Chinese Medicine from February 2021 to June 2022 were divided into a control group(50 cases,routine basic treatment+traditional Chinese medicine acupoint application and ironing)and an observation group(50 cases,routine basic treatment+traditional Chinese medicine acupoint application and ironing+Jianpi Zhuyu Formula treatment),all of which were continuously treated for 3 months.The clinical efficacy at 3 months of treatment,renal function indexes and hemorheology levels before treatment and at 3 months of treatment were compared.And the occurrence of adverse reactions during treatment was counted.Results The total effective rate of the control group was lower than that of the observation group(P<0.05).After 3 months of treatment,the control group showed higher levels of blood urea nitrogen,24-hour urine protein quantification,and blood creatinine compared to the observation group(P<0.05).After 3 months of treatment,the levels of fibrinogen,D-dimer,and plasma viscosity in the control group were higher than those in the observation group(P<0.05).There was no difference in the incidence of adverse reactions between the two groups during treatment(P>0.05).Conclusion Jianpi Zhuyu Formula combined with traditional Chinese medicine acupoint application and ironing has a significant clinical effect on senile idiopathic membranous nephropathy with spleen deficiency and kidney stasis syndrome,which is helpful to alleviate the symptoms of patients,improve the level of renal function and hemorheology indicators,and does not significantly increase adverse reactions.

Jianpi Zhuyu formulatraditional Chinese medicine acupoint application and ironingidiopathic membranous nephropathyspleen deficiency and kidney stasis syndrome

朱亚歌

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新密市中医院糖尿病肾病科,河南郑州 452370

健脾逐瘀方 中药穴位敷熨 特发性膜性肾病 脾虚肾瘀证

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(1)
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