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膀胱癌术后尿路感染的临床特点及影响因素

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目的 探讨膀胱癌术后尿路感染临床特点及有关影响因素.方法 选取2018年1月至2023年5月于医院接受膀胱癌切除术治疗的256例膀胱癌患者为研究对象,根据术后是否发生尿路感染分组.比较两组临床资料,通过logistic回归方程分析膀胱癌术后尿路感染相关危险因素.结果 256例膀胱癌术后有49例(19.14%)发生尿路感染.两组糖尿病、膀胱冲洗时间及血清C反应蛋白(CRP)、降钙素原(PCT)、诱导型一氧化氮合酶(iNOS)、干扰素-γ(IFN-γ)水平差异有统计学意义(P<0.05).糖尿病、膀胱冲洗时间(≥2 d)及血清CRP、PCT、iNOS、IFN-γ水平为胱癌患者术后发生尿路感染的危险因素(P<0.05).结论 糖尿病、膀胱冲洗时间及血清CRP、PCT、iNOS、IFN-γ水平均为膀胱癌术后尿路感染影响因素,临床需加以针对性防范和干预,促进预后改善.
Clinical Characteristics and Influencing Factors of Urinary Tract Infection After Bladder Cancer Surgery
Objective To investigate the clinical features and related factors of urinary tract infection after bladder cancer surgery.Methods A total of 256 patients with bladder cancer who underwent bladder cancer resection in hospital from January 2018 to May 2023 were divided into groups according to whether urinary tract infection occurred after surgery.The clinical data of the two groups were compared,and the risk factors of urinary tract infection after bladder cancer surgery were analyzed by logistic regression equation.Results Urinary tract infection occurred in 49 of 256 cases(19.14%)of bladder cancer after operation.Diabetes,bladder flushing time and serum C-reactive protein(CRP),procalcitonin(PCT),inducible nitric oxide synthase(iNOS),interferon-γ(IFN-y)between the two groups were statistically significant(P<0.05).Diabetes,bladder flushing time(≥2 days)and serum CRP,PCT,iNOS,IFN-γ were the risk factors for postoperative urinary tract infections in patients with cystitis(P<0.05).Conclusion Diabetes mellitus,bladder irrigation time and serum levels of CRP,PCT,iNOS and IFN-γ are all influencing factors of urinary tract infection after bladder cancer surgery.Clinical prevention and intervention should be targeted to promote the improvement of prognosis.

bladder cancersurgeryurinary tract infectioninfluencing factors

陈桂平、孙超群、翟晓乐

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平顶山市第一人民医院泌尿外科二病区,河南平顶山 467000

膀胱癌 手术 尿路感染 影响因素

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(2)
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