Influencing Factors of Adverse Cardiovascular Prognosis in Patients with Acute Coronary Syndrome
Objective To investigate the influencing factors of major adverse cardiovascular events(MACE)in the prognosis of patients with acute coronary syndrome(ACS).Methods A total of 200 patients with acute coronary syndrome admitted to the hospital from February 2019 to February 2022 were followed up for 1 year to observe the occurrence of MACE,and were grouped according to the follow-up results.General data[gender,age,body mass index(BMI),smoking history,drinking history,basic complications(hypertension,diabetes),family history of cardiovascular disease],clinical indicators(number of coronary artery lesions,number of stents implanted),cardiac function indicators[left ventricular ejection fraction(LVEF)],laboratory indicators[creatine kinase isoenzyme(CK-MB),troponin T(cTnT)].Draw receiver operating characteristic(ROC)curves to analyze the value of predicting MACE in ACS patients based on the number of coronary artery lesions,LVEF,CK-MB,and cTnT.Using multiple logistic regression analysis to identify the risk factors for MACE in ACS patients.Results After 1 year of follow-up,there were 40 cases(20.00％)in the MACE group and 160 cases(80.00％)in the non MACE group.There was no significant difference in gender,age,BMI,smoking history,drinking history,hypertension,diabetes,family history of cardiovascular disease,and the number of stents implanted between the two groups(P＞0.05).The number of coronary artery lesions in the group with MACE was higher than that in the group without MACE(P＜0.05),LVEF was lower than that in the group without MACE(P＜0.05),and CK-MB and cTnI were higher than those in the control group(P＜0.05).ROC analysis confirmed that LVEF,CK-MB,and cTnI can all predict the occurrence of MACE in ACS patients,with areas under the curves of 0.763,0.960,and 0.914,respectively(P＜0.05).Multivariate logistic regression analysis showed that the number of coronary artery lesions was＞1,LVEF≤ 53.35％,CK-MB≥173.81 U·L-1,and cTnI ≥0.62 μg·L-1 was risk factors for the occurrence of MACE in ACS patients(P＜0.05).Conclusion The number of coronary artery lesions was＞1,LVEF ≤53.35％,CK-MB≥173.81 U·L-1,and cTnI≥0.62 μg·L-1 was risk factors for the occurrence of MACE in ACS patients.
万方数据
维普
