Effect of Wenshen Antai Prescription Combined with Active Immunotherapy in Recurrent Spontaneous Abortion Patients with Kidney Deficiency and Blood Stasis Syndrome
Objective To study the effect of Wenshen Antai prescription combined with active immunotherapy in recurrent spontaneous abortion(RSA)patients with kidney deficiency and blood stasis syndrome.Methods A total of 66 RS A patients with kidney deficiency and blood stasis syndrome who were treated in the Affiliated Traditional Chinese Medicine Hospital of Nanyang Medical College from September 2020 to December 2021 were selected and divided into Western medicine group(accepted active immunotherapy)and combined group(active immunotherapy combined with Wenshen Antai prescription),with 33 cases in each group.Term delivery rate,blocking antibody conversion rate,traditional Chinese medicine syndrome score,Th1/Th2 cytokines[interleukin-2(IL-2),IL-10,IL-2/IL-10]and immune function[CD3+,CD8+,CD4+,CD4+/CD8+]levels before and after treatment were compared between the two groups.Results The term delivery rate of the combined group was higher than that of the Western medicine group(P＜0.05).After treatment,the traditional Chinese medicine syndrome score,the levels of IL-2 and IL-2/IL-10 of the combined group were lower than those of the Western medicine group,and IL-10 was higher than that in the Western medicine group(P＜0.05).After treatment,CD3+,CD4+,CD4+/CD8+in the combined group were lower than those in the Western medicine group,and CD8+was higher than that in the Western medicine group(P＜0.05).After treatment,the conversion rate of blocking antibody in the combined group was higher than that in the Western medicine group(P＜0.05).Conclusion The active immunotherapy combined with Wenshen Antai prescription can improve the term delivery rate of RSA with kidney deficiency and blood stasis syndrome,stabilize the Th1/Th2 balance,improve the body's immunity,promote the production of blocking antibodies and improve the symptoms.
Wenshen Antai prescriptionactive immunotherapyrecurrent spontaneous abortionfull term delivery rateTh1/Th2 equilibrium
万方数据
维普
